20 documents found, page 1 of 2

Adapting the sampling design of research surveys to improve the biomass estimat...

Research surveys are important to evaluate fishery resources’ spatial distribution and abundance. Although the underlying sampling is usually conceived with a focus on specific species, efficient designs can also collect data on secondary species. We present a framework to explore and evaluate the adequacy of alternative sampling designs for fishery research surveys aiming to maximize accuracy estimates of the ...

Analysis of Survival Data with Multiple Events

An important aim in biomedical studies is to study how an intermediate event and prognostic factors influence the course of disease of a patient. In most cases, the effect of the intermediate event is considered a timedependent covariate and studied using extensions of the Cox proportional hazards model. Additionally, many of these studies often involve several endpoints, making the traditional approaches much ...

Low-FODMAP Diet and Its Role in Irritable Bowel Syndrome (IBS) Management

<jats:title>Abstract</jats:title><jats:sec id="S0029665120000956_sec_a1" sec-type="intro"><jats:title>Introduction</jats:title><jats:p>Irritable Bowel Syndrome (IBS) is a functional and multifactorial gastrointestinal disorder characterized by pain, abdominal distention and motility changes, currently diagnosed based on the Rome IV criteria. The efficacy of classic pharmacological, psychological and dietary tre...

Gastric cancer extracellular vesicles tune the migration and invasion of epithe...

Extracellular vesicles (EVs) secreted by tumor cells modulate recipient cells’ behavior, but their effects in normal cells from the tumor microenvironment remain poorly known. In this study, we dissected the functional impact of gastric cancer cell-derived EVs (GC-EVs), representative of distinct GC histotypes, on the behavior of normal isogenic epithelial and mesenchymal cells. GC-EVs were isolated by differen...

Trade-Offs of Escherichia coli Adaptation to an Intracellular Lifestyle in Macr...

The bacterium Escherichia coli exhibits remarkable genomic and phenotypic variation, with some pathogenic strains having evolved to survive and even replicate in the harsh intra-macrophage environment. The rate and effects of mutations that can cause pathoadaptation are key determinants of the pace at which E. coli can colonize such niches and become pathogenic. We used experimental evolution to determine the s...

Dermatomiosite: desafios no tratamento?

Chorioangioma of the placenta.

Chorioangioma is the most frequent nontrophoblastic tumour of the placenta, with a reported incidence ranging from 0.01% to 1.3%. The authors describe three cases of placental chorioangiomas, two of these diagnosed prenatally by ultrasound, and the clinical implications for both mother and fetus. Premature delivery and hydramnios were the obstetric complications associated with these vascular tumours. We confir...

An analysis of plasma histaminase in schizophrenic patients and its relationshi...

Previous studies have investigated putative alterations in histamine and histamine receptors in schizophrenia, and evidence in favour of the role of this amine as a neurotransmitter or as a neuromodulator was found. In the present study the activity of plasmatic histaminase was analysed, with histamine and with cadaverine as substrates, in a group of 23 schizophrenic patients and compared with that of healthy c...

Activity of beta-N-acetylglucosaminidase in chronic alcoholic liver disease.

Serum N-acetyl-B-glucosaminidase (NAG) activity was determined in a control group of 76 normal people and in 23 patients with hepatic cirrhosis: 15 non-compensated patients and 8 with compensated chronic liver fibrosis. NAG is significantly increased in the non-compensated group--mean value of 931.67 units vs 637.71 units for the controls (p less than 0.001). There is no significant elevation regarding the comp...

Microalbuminuria in type I and type II diabetics without hypertension. A preview.