Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Serine Protease 2 (TMPRSS2), and Furin were known to be key players in the SARS-CoV-2 infection, and the thyroid gland was revealed to be one of the relevant targets of the virus. Regardless of the viral infection, the expression of these molecules in the thyroid gland and their putative role in the neoplastic transformation of the thyrocytes has not been th...
ATRX mutations occur in up to 17% of human pancreatic neuroendocrine tumours (PanNETs), and recent evidence points towards its inability to drive PanNET formation in mouse pancreas while predisposing individuals to inflammageing. Aiming to explore the additional non-tumourigenic consequences of Atrx deletion, we characterised an aged series of Atrx conditional disruption in β cells using the Pdx1 promoter. Homo...
A Terapia de Pressão Negativa Ultraportátil (TPNUP) com tecnologia hidrofiber de 80 mmHG, é um tratamento não invasivo aplicado em feridas agudas/crónicas, pouco exsudativas e sem sinais locais de infeção. Tem como objetivo reduzir o tempo de cicatrização, com o menor número de tratamentos e em ambiente ambulatório. A possibilidade de manter o mesmo aparelho durante 30 dias, permite também a redução de custos.