3 documents found, page 1 of 1
Lipid Antigen Presentation by CD1b and CD1d in Lysosomal Storage Disease Patients
Pereira, C.; Pérez-Cabezas, B.; Ribeiro, H.; Maia, M.; Cardoso, M.; Dias, A.; Azevedo, O.; Ferreira, M.; Garcia, P.; Rodrigues, E.; Castro-Chaves, P.The lysosome has a key role in the presentation of lipid antigens by CD1 molecules. While defects in lipid antigen presentation and in invariant Natural Killer T (iNKT) cell response were detected in several mouse models of lysosomal storage diseases (LSD), the impact of lysosomal engorgement in human lipid antigen presentation is poorly characterized. Here, we analyzed the capacity of monocyte-derived dendriti...
Predictors of in-hospital outcome in takotsubo cardiomyopathy, a multicenter study
Calvo, A. L. Ana; Azevedo, O.; Santos, R. P.; Almeida, A. R.; Craveiro, N.; Picarra, B.; Lima, R.; Reis, L.; Marmelo, B.; Marreiros, A.; Marques, NunoTakotsubo cardiomyopathy (TC) is characterized by a transient left ventricular (LV) dysfunction in the absence of significant coronary artery disease. The predictors of prognosis of TC are not yet fully established
Screening of Lysosomal acid lipase deficiency in patients with severe dyslipide...
Azevedo, O.; Marques, N.; Antunes, H.; Azevedo, Pedro; Oliveira, M.; Bento, D.; Guedes, J.; Marmelo, B.; Faria, R.; Correia, E.Objectives: To determine the prevalence of Lysosomal Acid Lipase (LAL) deficiency in patients with severe dyslipidemia and premature coronary heart disease.