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Portuguese Recommendations for the Use of Biological and Targeted Synthetic Dis...

Fernandes, BM; Guimarães, F; Almeida, DE; Neto, A; Tavares-Costa, J; Roxo Ribeiro, A; Quintal, A; Pereira, JP; Silva, L; Nóvoa, TS; Faustino, A; Vaz, C

Objective: To update the recommendations for the treatment of rheumatoid arthritis (RA) with biological and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs), endorsed by the Portuguese Society of Rheumatology (SPR). Methods: These treatment recommendations were formulated by Portuguese rheumatologists taking into account previous recommendations, new literature evidence and consen...


Scaling-Up Digital Follow-Up Care Services: Collaborative Development and Imple...

Azevedo, S; Guede-Fernández, F; Hafe, F; Dias, P; Lopes, I; Cardoso, N; Coelho, P; Santos, J; Fragata, J; Vital, C; Semedo, H; Gualdino, A; Londral, A

Background: COVID-19 increased the demand for Remote Patient Monitoring (RPM) services as a rapid solution for safe patient follow-up in a lockdown context. Time and resource constraints resulted in unplanned scaled-up RPM pilot initiatives posing risks to the access and quality of care. Scalability and rapid implementation of RPM services require social change and active collaboration between stakeholders. The...


Predictive Factors of Relapse After Methotrexate Discontinuation in Juvenile Id...

Azevedo, S; Tavares-Costa, J; Melo, AT; Freitas, R; Cabral, M; Conde, M; Aguiar, F; Neto, A; Mourão, AF; Oliveira-Ramos, F; Santos, MJ; Peixoto, D

Objective: To identify predictive factors of relapse after discontinuation of Methotrexate (MTX) in Juvenile Idiopathic Arthritis (JIA) patients with inactive disease. Methods: We conducted a prospective multicenter cohort study of patients diagnosed with JIA using real world data from the Portuguese national register database, Reuma.pt. Patients with JIA who have reached JADAS27 inactive disease and discontinu...


Developing and Validating High-Value Patient Digital Follow-Up Services: a Pilo...

Londral, A; Azevedo, S; Dias, P; Ramos, C; Santos, J; Martins, F; Silva, R; Semedo, H; Vital, C; Gualdino, A; Falcão, J; Lapão, LV; Coelho, P

Background: The existing digital healthcare solutions demand a service development approach that assesses needs, experience, and outcomes, to develop high-value digital healthcare services. The objective of this study was to develop a digital transformation of the patients' follow-up service after cardiac surgery, based on a remote patient monitoring service that would respond to the real context challenges. Me...


Portuguese recommendations for the use of biological and targeted synthetic dis...

Fernandes, Bruno Miguel; Guimarães, F; Almeida, DE; Neto, A; Tavares-Costa, J; Ribeiro, AR; Quintal, Alberto; Pereira, JP; Silva, L; Nóvoa, TS

Objective: To update the recommendations for the treatment of rheumatoid arthritis (RA) with biological and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs), endorsed by the Portuguese Society of Rheumatology (SPR). Methods: These treatment recommendations were formulated by Portuguese rheumatologists taking into account previous recommendations, new literature evidence and consen...


Portuguese Consensus on Diagnosis, Treatment, and Management of Anemia in Pedia...

Lopes, AI; Azevedo, S; Cabral, J; Ferreira, MG; Sande-Lemos, P; Ferreira, R; Trindade, E; Lima, R; Antunes, H

Anemia is a common extraintestinal manifestation of inflammatory bowel disease (IBD), both in pediatric and in adult patients. Iron deficiency is the main cause of anemia in patients with IBD. Anemia is a clinically relevant comorbidity, with impact on patients' quality of life and it should be timely diagnosed and adequately treated. Currently, an active treatment approach is the recommended strategy, with evi...


Remission and low disease activity matrix tools: results in real-world rheumato...

Ganhão, S; Lucas, R; Fonseca, JE; Santos, MJ; Gonçalves, DR; Madeira, N; Silva, C; Dourado, E; Freitas, R; Rodrigues, J; Azevedo, S; Rocha, TM

Background: Remission/ low disease activity (LDA) are the main treatment goals in rheumatoid arthritis (RA) patients. Two tools showing the ability to predict golimumab treatment outcomes in patients with RA were published. Objectives: To estimate the real-world accuracy of two quantitative tools created to predict RA remission and low disease activity. Methods: Multicenter, observational study, using data from...


Effect of Indoor Air Quality of Day Care Centers in Children with Different Pre...

Carreiro-Martins, P; Papoila, AL; Caires, I; Azevedo, S; Cano, MM; Virella, D; Leiria-Pinto, P; Teixeira, JP; Rosado-Pinto, J; Annesi-Maesano, I

Scarce information is available about the relationships between indoor air quality (IAQ) at day care centers (DCC), the estimated predisposition for asthma, and the actual wheezing susceptibility. METHODS: In the Phase II of ENVIRH study, 19 DCC were recruited after cluster analysis. Children were evaluated firstly using the ISAAC questionnaire and later by a follow-up questionnaire about recent wheezing. A pos...


Effect of Indoor Air Quality of Day Care Centers in children with Different Pre...

Carreiro-Martins, P; Papoila, AL; Caires, I; Azevedo, S; Cano, MM; Virella, D; Leiria-Pinto, P; Teixeira, JP; Rosado-Pinto, J; Annesi-Maesano, I

BACKGROUND: Scarce information is available about the relationships between indoor air quality (IAQ) at day care centers (DCC), the estimated predisposition for asthma, and the actual wheezing susceptibility. METHODS: In the Phase II of ENVIRH study, 19 DCC were recruited after cluster analysis. Children were evaluated firstly using the ISAAC questionnaire and later by a follow-up questionnaire about recent whe...


Effect of indoor air quality of day care centers in children with different pre...

Carreiro Martins, P; Papoila, AL; Caires, I; Azevedo, S; Cano, MM; Leiria-Pinto, P; Teixeira, JP; Rosado-Pinto, J; Annesi Maesano, I; Neuparth, N

BACKGROUND:Scarce information is available about the relationships between indoor air quality (IAQ) at day care centers (DCC), the estimated predisposition for asthma, and the actual wheezing susceptibility. METHODS:In the Phase II of ENVIRH study, 19 DCC were recruited after cluster analysis. Children were evaluated firstly using the ISAAC questionnaire and later by a follow-up questionnaire about recent wheez...


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