ABSTRACT: Objective: To analyze the spatial distribution of the four-year cancer mortality rates in the state of Mato Grosso, Brazil, from 2000 to 2015. Methodology: Ecological design study, in which mortality from neoplasia was analyzed, from 2000 to 2015, for the municipalities of Mato Grosso State. Mortality rates due to cancer were calculated by the ratio of the sum of deaths by cancer in each quadrennium, ...