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Crotacetin, a Novel Snake Venom C-Type Lectin Homolog of Convulxin, Exhibits an...

Rádis-Baptista, Gandhi; Moreno, Frederico Bruno Mendes Batista; Nogueira, Lucas de Lima; Martins, Alice M. C.; Toyama, Daniela de Oliveira

Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins that are capable of interfering with blood stasis. A very well-studied svC-type lectin is the heterodimeric toxin, convulxin (CVX), from the venom of South American rattlesnake Crotalus durissus terrificus. CVX is able to activate platelets and induce their aggregation by acting via p62/GPVI collagen receptor. By using polymerase chain reac...

Date: 2021   |   Origin: Oasisbr
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