Encontrados 24 documentos, a visualizar página 1 de 3
Breaking the virus: yeast glucans as an effective alternative to acyclovir in H...
Tavares-Valente, Diana; Moreira, Helena; Sousa, Pedro; Amorim, Manuela; Conde, António; Pintado, Manuela; Fernandes, João; Azevedo-Silva, JoãoGlucans, structural polysaccharides in the yeast cell wall, are known for their biological and immunomodulatory capacities, helping in prevention and management of infections. Herpes simplex virus type 1 (HSVI) is a prevalent infection that causes great comorbidity and is challenging to treat due to the adverse effects of standard antiviral drugs like acyclovir. This study assessed the potential of yeast glucan...
Silica microparticles from sugarcane by-products as an encapsulation system for...
Costa, Joana R.; Costa, Ana Helena; Azevedo-Silva, João; Tavares-Valente, Diana; Sousa, Sérgio C.; Neto, Tânia; Pintado, Manuela E.The encapsulation of retinol within silica microparticles has emerged as a promising opportunity in the realm of cosmetic and pharmaceutical formulations, driven by the need to reinforce the photoprotection and oxidation stability of retinol. This work examines the process of encapsulating retinol into silica microparticles. The association efficiency, microparticle size, molecular structure, morphology, oxidat...
Elevating skincare science: grape seed extract encapsulation for dermatological...
Castro, Maria Leonor; Azevedo-Silva, João; Valente, Diana; Machado, Adriana; Ribeiro, Tânia; Ferreira, João Paulo; Pintado, Manuela; Ramos, Oscar L.The skin is the largest organ in the human body and serves multiple functions such as barrier protection and thermoregulation. The maintenance of its integrity and healthy structure is of paramount importance. Accordingly, technological advances in cosmetic sciences have been directed towards optimizing these factors. Plant-derived ingredients have been explored for their bioactivity profiles and sustainable so...
Circular economyeast: saccharomyces cerevisiae as a sustainable source of gluca...
Sousa, Pedro; Tavares-Valente, Diana; Pereira, Carla F.; Pinto-Ribeiro, Inês; Azevedo-Silva, João; Madureira, Raquel; Ramos, Óscar L.; Pintado, ManuelaGlucans, a polysaccharide naturally present in the yeast cell wall that can be obtained from side streams generated during the fermentation process, have gained increasing attention for their potential as a skin ingredient. Therefore, this study focused on the extraction method to isolate and purify water-insoluble glucans from two different Saccharomyces cerevisiae strains: an engineered strain obtained from s...
Chaves thermal spring water impact on skin health: potential cosmetic application
Pinto-Ribeiro, Inês; Castro, Cláudia; Rocha, Pedro Emanuel; Carvalho, Maria João; Pintado, Ana; Mendes, Adélia; Pedrosa, Sílvia Santos; Capeto, PaulaSince ancient times, thermal spring water has been proven to be beneficial to the skin and to improving dermatologic disorders, explaining its incorporation into cosmetic formulations as an active ingredient. Chaves thermal spring water, from northern Portugal, has been used as a local spa since Roman times, and its customers are satisfied with its medicinal quality. Despite the lack of published evidence on it...
Exploring cannabidiol (CBD) and cannabigerol (CBG) safety profile and skincare ...
Luz-Veiga, Mariana; Mendes, Adélia; Tavares-Valente, Diana; Amorim, Manuela; Conde, António; Pintado, Manuela Estevez; Moreira, Helena R.Cannabinoids have long been known for their bioactive properties, with their topical application as anti-inflammatory compounds being at the forefront of research for the past decade. Concurrently, the cosmetic market is a fast-growing industry in constant need of new biomolecules. In this work, we studied the safety profile for topical applications of two cannabinoids: cannabidiol (CBD) and cannabigerol (CBG) ...
A paradigm shift in skincare through the power of grape seed-loaded liposomes
Castro, Maria Leonor de; Azevedo-Silva, João; Valente, Diana; Machado, Adriana; Ribeiro, Tânia; Ferreira, João Paulo; Pintado, Manuela; Ramos, OscarThe skin undergoes natural aging and is prone to various conditions/pathologies due to constant exposure to environmental stressors and abrasions. The cosmetic industry has revolutionized skincare, each time in a higher trend for natural and organic products. The growing trend of clean beauty, driven by consumer demand for non-toxic and environmentally friendly products, is increasingly intertwined with sustain...
Exploring yeast glucans for vaccine enhancement: sustainable strategies for ove...
Azevedo-Silva, João; Amorim, Manuela; Tavares-Valente, Diana; Sousa, Pedro; Mohamath, Randolph; Voigt, Emily A.; Guderian, Jeffrey A.; Kinsey, RobertVaccine adjuvants are important for enhancing vaccine efficacy, and although aluminium salts (Alum) are the most used, their limited ability to induce specific immune responses has spurred the search for new adjuvants. However, many adjuvants fail during product development due to manufacturability, supply, stability, or safety concerns. This work hypothesizes that protein-free yeast glucans can be used as vacc...
Elevating skincare science: grape seed-extract encapsulation for dermatological...
Castro, Maria Leonor de; Azevedo-Silva, João; Valente, Diana; Machado, Adriana; Ribeiro, Tânia; Ferreira, João Paulo; Pintado, Manuela; Ramos, Oscar L.The skin is the largest organ in the human body and serves multiple functions such as barrier protection and thermoregulation. The maintenance of its integrity and healthy structure is of paramount importance. Accordingly, technological advances in cosmetic sciences have been directed towards optimizing these factors. Plant-derived ingredients have been explored for their bioactivity profiles and sustainable so...
Anti-aging potential of a novel ingredient derived from sugarcane straw extract...
Carvalho, Maria João; Pedrosa, Sílvia Santos; Mendes, Adélia; Azevedo-Silva, João; Fernandes, João; Pintado, Manuela; Oliveira, Ana L. S.Natural and sustainable anti-aging ingredients have gained attention from the cosmetic industry. This study evaluated the anti-aging potential of a sugarcane straw extract-based (SSE) cosmetic ingredient. First, cytotoxicity tests were assessed in keratinocytes and fibroblast cell lines, and sensitization was carried out through the direct peptide reactivity assay. Subsequently, various anti-aging properties we...