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The contribution of second primary cancers to the mortality of patients with a ...

Gonçalves, E; Fontes, F; Rodrigues, JR; Calisto, R; Bento, MJ; Lunet, N; Morais, S

Purpose: Second primary cancers (SPCs) are estimated to affect nearly 5% of patients with breast cancer within 10 years of their diagnosis. This study aimed to estimate the contribution of SPCs to the mortality of patients with a breast first primary cancer (FPC). Methods: A population-based cohort of 17,210 patients with a breast FPC diagnosed between 2000 and 2010 was followed for SPCs (31/12/2015) and vital ...


Second primary cancers among females with a first primary breast cancer: a popu...

Gonçalves, E; Fontes, F; Rodrigues, JR; Calisto, R; Bento, MJ; Lunet, N; Morais, S

"Purpose To estimate the incidence rate of second primary cancers (SPCs) and the cumulative incidence of metachronous [diagnosed > 2 months after a first primary cancer (FPC)] SPCs in patients with a breast FPC, and to compare the incidence of SPC [overall, synchronous (≤ 2 months of the FPC) and metachronous] with that expected in the general female population. Methods A cohort of patients with a breast FPC fr...


Risk and Survival of Third Primary Cancers in a Population-Based Cohort of Brea...

Morais, S; Gonçalves, E; Fontes, F; Rodrigues, J; Calisto, R; Bento, MJ; Lunet, N

Introduction: The growing number of women diagnosed with breast cancer (BCa) together with high survival has resulted in an increasing population of survivors at risk of subsequent primary cancers. This study aimed to estimate the long-term risk and survival of third primary cancers (TPCs) among females with a first primary BCa. Methods: Breast first primary cancers (FPCs) from the Portuguese North Region Cance...


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