Multinucleated cell angiohistiocytoma (MCAH) is a rare clinical entity whose pathogenesis is not fully understood. It is more common in middle-aged women and is characterized by erythematoviolaceous papules or nodules, usually asymptomatic and predominantly located in the extremities. Histopathology is essential for making the diagnosis, consisting of typical alterations in the dermis, namely the proliferation ...
The herpes simplex virus is a common cause of genital ulcers. In the immunocompromised, it may have an atypical presentation, with exuberant lesions, frequently resulting in resistance to the mainstream therapeutic options, and a consequent prolonged course.A 25-year-old male with a previous history of common variable immunodeficiency, presented with herpetic extensive genital ulcerations on the inguinoscrotal ...
Ductal eccrine carcinoma is a rare and aggressive skin cancer. Its diagnosis implies the exclusion of a primary adenocarcinoma located elsewhere with cutaneous metastization, as the histological and immunohistochemical analysis are not sufficient by themselves. We report the clinical case of a 75-year-old male with a 3 cm width tumor located on the right hemiface, which was excised and whose histology and immun...
Introduction: Atypical fibroxanthoma (AFX) is a rare cutaneous tumor without a completely defined histogenesis which frequently develops on head and neck of elderly people. Its diagnosis is histological, of exclusion with other tumors with identical morphology. Despite its classical benign behavior some rare cases reporting distant metastasis classified it on intermediate malignancy.Material and methods: We pre...
Introduction: The incidence of malignant melanoma has been rising. Therefore, the knowledge of its prevalence is very important. The authors intended to study the prevalence, demographic variables and the clinical features of the malignant melanoma diagnosed in their department.Material and methods: A retrospective study of the MM diagnosed between 2006 and 2013 was performed. The data was statistically an anal...
Propylthiouracil (PTU) is widely used in the treatment of Hyperthyroidism. Usually well tolerated, it is though associated with antineutrophil cytoplasmic antibodies (ANCA) and, less frequently, with late-onset ANCA positive vasculitis. The authors describe the clinical case of a 45-year-old female patient with Graves’ disease for which she was being treated with PTU since 3 years before, who developed an ANCA-...
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Introduction: Granuloma faciale is an uncommon disease. Clinical and histopathological features have been described only in case reports or small series.Material and methods: A retrospective study from 2001 to 2012 of patients with granuloma faciale diagnosed at the Department of Dermatology of Garcia de Orta Hospital was performed. The demographic, clinical and histopathological features were evaluated and a r...
Pachydermodactylyis is a rare form of fibromatosis affecting the lateral aspects of the first phalanges of the hands. Although idiopathic by definition, frequently a repetitive mechanical trauma is identifiable as its cause. The authors describe two case reports of this condition.; A paquidermodactilia é uma forma rara de fibromatose que envolve a face lateral das primeiras falanges dos dedos das mãos. Apesar d...
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