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Global Prevalence of Aspirin Use for Primary Prevention of Cardiovascular Disea...

Yoo, SGK; Chung, GS; Bahendeka, SK; Sibai, AM; Damasceno, A; Farzadfar, F; Rohloff, P; Houehanou, C; Norov, B; Karki, KB; Azangoukhyavy, M; Marcus, ME

The role of aspirin in the primary prevention of atherosclerotic cardiovascular disease (CVD) is not clear, with recent clinical trials evaluating aspirin for primary prevention demonstrating both modest benefits and risks associated with its use [1]. Aspirin is not routinely recommended for primary prevention of CVD. Understanding patterns of aspirin use can inform strategies to promote guideline-concordant th...


Diagnostic testing for hypertension, diabetes, and hypercholesterolaemia in low...

Ochmann, S; von Polenz, I; Marcus, ME; Theilmann, M; Flood, D; Agoudavi, K; Aryal, KK; Bahendeka, S; Bicaba, B; Bovet, P; Campos Caldeira Brant, L

Background Testing for the risk factors of cardiovascular disease, which include hypertension, diabetes, and hypercholesterolaemia, is important for timely and effective risk management. Yet few studies have quantified and analysed testing of cardiovascular risk factors in low-income and middle-income countries (LMICs) with respect to sociodemographic inequalities. We aimed to address this knowledge gap. Method...


Aspirin for Secondary Prevention of Cardiovascular Disease in 51 Low-, Middle-,...

Yoo, SGK; Chung, GS; Bahendeka, SK; Sibai, AM; Damasceno, A; Farzadfar, F; Rohloff, P; Houehanou, C; Norov, B; Karki, KB; Azangou-Khyavy, M; Marcus, ME

"Importance Aspirin is an effective and low-cost option for reducing atherosclerotic cardiovascular disease (CVD) events and improving mortality rates among individuals with established CVD. To guide efforts to mitigate the global CVD burden, there is a need to understand current levels of aspirin use for secondary prevention of CVD. Objective To report and evaluate aspirin use for secondary prevention of CVD a...


Association between country preparedness indicators and quality clinical care f...

Davies, JI; Reddiar, SK; Hirschhorn, LR; Ebert, C; Marcus, ME; Seiglie, JA; Zhumadilov, Z; Supiyev, A; Sturua, L; Silver, BK; Sibai, AM

Background: Cardiovascular diseases are leading causes of death, globally, and health systems that deliver quality clinical care are needed to manage an increasing number of people with risk factors for these diseases. Indicators of preparedness of countries to manage cardiovascular disease risk factors (CVDRFs) are regularly collected by ministries of health and global health agencies. We aimed to assess wheth...


The state of hypertension care in 44 low-income and middle-income countries: a ...

Geldsetzer, P; Manne-Goehler, J; Marcus, ME; Ebert, C; Zhumadilov, Z; Wesseh, CS; Tsabedze, L; Supiyev, A; Sturua, L; Bahendeka, SK; Sibai, AM

Background Evidence from nationally representative studies in low-income and middle-income countries (LMICs) on where in the hypertension care continuum patients are lost to care is sparse. This information, however, is essential for effective targeting of interventions by health services and monitoring progress in improving hypertension care. We aimed to determine the cascade of hypertension care in 44 LMICs—a...


Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, ...

El Bcheraoui, C; Wang, H; Charara, R; Khalil, I; Moradi-Lakeh, M; Afshin, A; Collison, M; Daoud, F; Chew, A; Krohn, K; Carter, A; Foreman, K; He, F

Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with di...


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