3 documents found, page 1 of 1
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-...
Cruz, Rossilene Conceição da Silva; Bührer-Sékula, Samira; Penna, Gerson Oliveira; Moraes, Maria Elisabete Amaral de; Gonçalves, Heitor de SáBACKGROUND: The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs. OBJECTIVE: Describe adverse effects due to MDT in U-MDT/CT-BR, comparing the uniform regimen (U-MDT) to the current WHO regimen (R-MDT). Patients and methods: After operational classification, ...
Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): results...
Penna, Gerson Oliveira; Bührer-Sékula, Samira; Kerr, Ligia Regina Franco Sansigolo; Rodrigues, Laura Cunha; Araújo, Marcelo Grossi deBackground Leprosy control is based on early diagnosis and multidrug therapy. For treatment purposes, leprosy patients can be classified as paucibacillary (PB) or multibacillary (MB), according to the number of skin lesions. Studies regarding a uniform treatment regimen (U-MDT) for all leprosy patients have been encouraged by the WHO, rendering disease classification unnecessary. Methodology and findings An ind...
A clinical trial for uniform multidrug therapy for leprosy patients in Brazil :...
Penna, Gerson Oliveira; Pontes, Maria Araci de Andrade; Cruz, Rossilene Conceição da Silva; Gonçalves, Heitor de Sá; Penna, Maria Lúcia FernandesLeprosy will continue to be a public health problem for several decades. The World Health Organization (WHO) recommends that, for treatment purposes, leprosy cases be classified as either paucibacillary or multibacillary (MB). A uniform leprosy treatment regimen would simplify treatment and halve the treatment duration for MB patients. The clinical trial for uniform multidrug therapy (U-MDT) for leprosy patient...