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Lithium ameliorates sleep deprivation-induced mania-like behavior, hypothalamic...
Valvassori, Samira S.; Resende, Wilson R.; Dal-Pont, Gustavo; Sangaletti-Pereira, Heron; Gava, Fernanda F.; Peterle, Bruna R.; Carvalho, André F.Objectives: The goal of the present study was to investigate the effects of lithium administration on behavior, oxidative stress parameters and cytokine levels in the periphery and brain of mice subjected to an animal model of mania induced by paradoxical sleep deprivation (PSD). Methods: Male C57 mice were treated with saline or lithium for 7 days. The sleep deprivation protocol started on the 5th day during f...
Data: 2017
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Origem: Oasisbr