Infection by the protozoan Trypanosoma cruzi causes Chagas disease cardiomyopathy (CCC) and can lead to arrhythmia, heart failure and death. Chagas disease affects 8 million people worldwide, and chronic production of the cytokines IFN-γ and TNF-α by T cells together with mitochondrial dysfunction are important players for the poor prognosis of the disease. Mitochondria occupy 40% of the cardiomyocytes volume a...
Made available in DSpace on 2021-07-14T10:39:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-14. Added 1 bitstream(s) on 2021-07-14T11:35:16Z : No. of bitstreams: 1 S0066-782X2021000701174.pdf: 1547521 bytes, checksum: 75b35df7e6cfe36a77d4c58255a0eb69 (MD5); Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Instituto do Coração; Pontifícia Universidade Católica de Curitib...
Frente à pandemia da doença causada pelo novo coronavírus (COVID-19), o manejo do paciente com fator de risco e/ou doença cardiovascular é desafiador nos dias de hoje. As complicações cardiovasculares evidenciadas nos pacientes com COVID-19 resultam de vários mecanismos, que vão desde lesão direta pelo vírus até complicações secundárias à resposta inflamatória e trombótica desencadeada pela infecção. O cuidado ...
In face of the pandemic of the novel coronavirus disease 2019 (COVID-19), the management of patients with cardiovascular risk factors and/or disease is challenging. The cardiovascular complications evidenced in patients with COVID-19 derive from several mechanisms, ranging from direct viral injury to complications secondary to the inflammatory and thrombotic responses to the infection. The proper care of patien...
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Made available in DSpace on 2020-12-12T00:59:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01; Purpose: The purpose of this study was to investigate the hemodynamic and cardiorespiratory adaptations to exercise in individuals with heart transplantation with evidence of cardiac reinnervation (cardiac reinnervation group) versus without evidence of cardiac reinnervation (no cardiac reinnervation gr...