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CuMV VLPs Containing the RBM from SARS-CoV-2 Spike Protein Drive Dendritic Cell...

Sebastião, Ana Isabel; Mateus, Daniela; Carrascal, Mylène A.; Sousa, Cátia; Cortes, Luísa; Bachmann, Martin F; do Carmo, Anália; Matos, Ana M.

Dendritic cells (DCs) are the most specialized and proficient antigen-presenting cells. They bridge innate and adaptive immunity and display a powerful capacity to prime antigen-specific T cells. The interaction of DCs with the receptor-binding domain of the spike (S) protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pivotal step to induce effective immunity against the S protei...


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