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Antibacterial Photodynamic Inactivation of Antibiotic-Resistant Bacteria and Bi...

Vinagreiro, Carolina dos Santos; Zangirolami, Amanda; Schaberle, Fábio António; Nunes, Sandra Cristina da Cruz; Blanco, Kate C; Inada, Natalia M.

Gram-negative bacteria and bacteria in biofilms are very difficult to eradicate and are the most antibiotic-resistant bacteria. Therapeutic alternatives less susceptible to mechanisms of resistance are urgently needed to respond to an alarming increase of resistant nosocomial infections. Antibacterial photodynamic inactivation (PDI) generates oxidative stress that triggers multiple cell death mechanisms that ar...

Date: 2020   |   Origin: Estudo Geral - Universidade de Coimbra
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