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Patterns of dosage regimen instructions regarding topical medicines: how is the...

Teixeira, Ana; Teixeira, Maribel; Bento, Carmen; Azevedo, Luís Filipe; Vasconcelos, Viviana; Bahia, Maria Fernanda; Torres, Tiago; Morna, Carla

Background: The communication of dosage regimen instructions by physicians is of utmost importance on treatment adherence. Few studies until now have approached the topical treatment adherence subject. Objective: This study aims the characterization of dosage regimen instructions given by physicians and the assessment of chronic dermatological patients’ perception regarding these instructions. Methods: Two inst...


Knowledge and practices of community pharmacists in topical dermatological trea...

Teixeira, Ana; Teixeira, Maribel; Herdeiro, Maria Teresa; Vasconcelos, Viviana; Correia, Rita; Bahia, Maria Fernanda; Almeida, Isabel

The connection between pharmacists’ knowledge and practice on the provided information to patients about dermatoses and their treatment is insufficiently characterized. Furthermore, pharmacists’ contributions in counselling and in promoting adherence to topical treatment is not fully understood. This study has three main objectives. It aims to identify the knowledge and practices of pharmacists about dermatoses...


Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a...

Almeida, Isabel F.; Pinto, A.S.; Monteiro, C.; Monteiro, H.; Belo, L.; Fernandes, J.; Bento, A.R.; Duarte, T.L.; Garrido, J.; Bahia, Maria Fernanda

Toxic effects of ultraviolet (UV) radiation on skin include protein and lipid oxidation, and DNA damage. The latter is known to play a major role in photocarcinogenesis and photoaging. Many plant extracts and natural compounds are emerging as photoprotective agents. Castanea sativa leaf extract is able to scavenge several reactive species that have been associated to UV-induced oxidative stress. The aim of this...


Characterization of an antioxidant surfactant-free topical formulation containi...

Almeida, Isabel F.; Maleckova, Jitka; Saffi, Raquel; Monteiro, Helena; Góios, Filipa; Amaral, Maria Helena; Costa, Paulo Cardoso; Garrido, Jorge

Context: Inclusion of antioxidants in topical formulations can contribute to minimize oxidative stress in the skin, which has been associated with photoaging, several dermatosis and cancer. Objective: A Castanea sativa leaf extract with established antioxidant activity was incorporated into a semisolid surfactant-free formulation. The objective of this study was to perform a comprehensive characterization of th...


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