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Resveratrol-Based Nanoformulations as an Emerging Therapeutic Strategy for Cancer

Sharifi-Rad, J; Quispe, C; Mukazhanova, Z; Knut, E; Turgumbayeva, A; Kipchakbayeva, A; Seitimova, G; Mahomoodally, MF; Lobine, D; Koay, A; Wang, J

Resveratrol is a polyphenolic stilbene derivative widely present in grapes and red wine. Broadly known for its antioxidant effects, numerous studies have also indicated that it exerts anti-inflammatory and antiaging abilities and a great potential in cancer therapy. Regrettably, the oral administration of resveratrol has pharmacokinetic and physicochemical limitations such as hampering its effects so that effec...


Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Att...

Sharifi-Rad, J; Butnariu, M; Ezzat, SM; Adetunji, CO; Imran, M; Sobhani, SR; Tufail, T; Hosseinabadi, T; Ramírez-Alarcón, K; Martorell, M; Maroyi, A

Mushrooms have a significant role in human diet as functional food and as a nutraceutical resource. The combination of its umami flavor, protein, vitamins, minerals and carbohydrates has meant that mushrooms could be considered a cheap food source for a long time in many countries. Moreover, mushrooms contain an excellent variety of bioactive metabolites that can be successful in both prevention and treatment o...


Measurement of off-flavoring volatile compounds and microbial load as a probabl...

Rashid, A; Javed, I; Rasco, B; Sablani, S; Ayaz, M; Ali, MA; Abdullah, M; Imran, M; Gondal, TA; Afzal, MI; Atif, M; Salehi, B; Rodrigues, CF

Background: Multiple attempts have been conducted to correlate milk keeping quality with chemical, physical or bacteriological parameters. These methods only measure the chemical changes in milk produced by bacteria. Headspace solid-phase micro-extraction (HS-SPME) is an economic and recent method used to measure both volatile compounds and microbial load in milk, also allowing to keep the quality of the milk p...


Therapeutic potential of rosmarinic acid: A comprehensive review

Nadeem, M; Imran, M; Gondal, TA; Imran, A; Shahbaz, M; Amir, RM; Sajid, MW; Qaisrani, TB; Atif, M; Hussain, G; Salehi, B; Ostrander, EA; Martorell, M

Naturally occurring food-derived active ingredients have received huge attention for their chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) is a caffeic acid ester and a naturally-occurring phenolic compound in a number of plants belonging to the Lamiaceae family, such as Rosmarinus officinalis (rosemary) from which it was formerly isolated. RA intervenes in carcinogenesis...


Kaempferol: A Key Emphasis to Its Anticancer Potential

Imran, M; Salehi, B; Sharifi Rad, J; Gondal, TA; Saeed, F; Imran, A; Shahbaz, M; Fokou, PVT; Arshad, MU; Khan, H; Susana Guerreiro; Martins, N

A marked decrease in human cancers, including breast cancer, bone cancer, and cervical cancer, has been linked to the consumption of vegetable and fruit, and the corresponding chemoprotective effect has been associated with the presence of several active molecules, such as kaempferol. Kaempferol is a major flavonoid aglycone found in many natural products, such as beans, bee pollen, broccoli, cabbage, capers, c...


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