3 documents found, page 1 of 1
mRNA profiling and donor association of mock casework samples: Results of a 3rd...
Hänggi, Nadescha Viviane; Amorim, António; Afonso Costa, Heloísa; Andersen, Jeppe Dyrberg; Kampmann, Marie-Louise; Courts, Cornelius; Neis, MaximilianSimultaneous identification and association of body fluids to donors can serve as a powerful tool in the criminal investigation of mixed traces. Massively parallel sequencing of mRNA targets not only identifies the origin of the body fluids but may also provide additional contextual information about the body fluid donors of a (binary) mixture using coding region SNPs (cSNPs). Within the European DNA Profiling ...
Body fluid identification and donor association of mock case samples: Results o...
Hänggi, Nadescha; Amorim, António; Afonso Costa, Heloísa; D. Andersen, Jeppe; Morling, Niels; Kampmann, Marie-Louise; Courts, Cornelius; Gosch, AnnicaThe European DNA Profiling Group (EDNAP) has previously evaluated the performance, robustness, and reproducibility of various mRNA markers for identifying body fluids using capillary electrophoresis (CE) and massively parallel sequencing (MPS) methods. MPS of mRNA targets is used for body fluid identification and provides information on who contributed which body fluid to a binary mixture, thereby adding import...
Toward male individualization with rapidly mutating y‐chromosomal short tandem ...
Ballantyne, Kaye N.; Ralf, Arwin; Aboukhalid, Rachid; Achakzai, Niaz M.; Anjos, Maria J.; Ayub, Qasim; Balažic, Jože; Ballantyne, JackRelevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are com monly used for testing close paternal relationships among individuals and populations, and for male lineage iden tification. However, even the widely used 17-loci Yfiler set cannot resolve individuals and populations completely. Here, 52 centers generated quality-controlled data of 13 rapidly mutating (RM) Y-STRs i...