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Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes:...

Fernandes, A; Avraam, D; Cadman, T; Dadvand, P; Guxens, M; Binter, A-C; Pinot de Moira, A; Nieuwenhuijsen, M; Duijts, L; Julvez, J; De Castro, M

Studies evaluating the benefits and risks of green spaces on children's health are scarce. The present study aimed to examine the associations between exposure to green spaces during pregnancy and early childhood with respiratory, cardiometabolic, and neurodevelopmental outcomes in school-age children. We performed an Individual-Participant Data (IPD) meta-analysis involving 35,000 children from ten European bi...


Physical activity, sedentary behaviour, and childhood asthma: a European collab...

Eijkemans, M; Mommers, M; Harskamp-van Ginkel, MW; Vrijkotte, TGM; Ludvigsson, J; Faresjö, Å; Bergström, A; Ekström, S; Grote, V; Koletzko, B

OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. SETTING: Ch...


Ambient air temperature exposure and foetal size and growth in three European b...

Essers, E; Granés, L; Delaney, S; Ballester, J; Santos, S; Petricola, S; Yang, TC; Fernández-Somoano, A; Bereziartua, A; Ballester, F; Tardón, A

Introduction: Ambient air temperature may affect birth outcomes adversely, but little is known about their impact on foetal growth throughout pregnancy. We evaluated the association between temperature exposure during pregnancy and foetal size and growth in three European birth cohorts. Methods: We studied 23,408 pregnant women from the English Born in Bradford cohort, Dutch Generation R Study, and Spanish INMA...


Maternal body mass index, gestational weight gain, and the risk of overweight a...

Voerman, E; Santos, S; Patro Golab, B; Amiano, P; Ballester, F; Barros, H; Bergström, A; Charles, MA; Chatzi, L; Chevrier, C; Chrousos, GP

Maternal obesity and excessive gestational weight gain may have persistent effects on offspring fat development. However, it remains unclear whether these effects differ by severity of obesity, and whether these effects are restricted to the extremes of maternal body mass index (BMI) and gestational weight gain. We aimed to assess the separate and combined associations of maternal BMI and gestational weight gai...


Fish and seafood consumption during pregnancy and the risk of asthma and allerg...

Stratakis, N; Roumeliotaki, T; Oken, E; Ballester, F; Barros, H; Basterrechea, M; Cordier, S; de Groot, R; den Dekker, HT; Duijts, L; Eggesbø, M

Background: It has been suggested that prenatal exposure to n-3 long-chain fatty acids protects against asthma and other allergy-related diseases later in childhood. The extent to which fish intake in pregnancy protects against child asthma and rhinitis symptoms remains unclear. We aimed to assess whether fish and seafood consumption in pregnancy is associated with childhood wheeze, asthma and allergic rhinitis...


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