2 documents found, page 1 of 1
In vitro metabolism of copalic and kaurenoic acids in rat and human liver micro...
Mauro, Mariana [UNESP]; da Silva, Rodrigo Moreira; de Campos, Michel Leandro; Bauermeister, Anelize; Lopes, Norberto PeporineMade available in DSpace on 2022-04-29T08:32:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Copalic (CA) and kaurenoic (KA) acids are the main diterpenes found in the oleoresin extracted from the copaiba tree (Copaifera sp). This study aimed to characterize the metabolism of CA and KA in rat and human liver microsomes using liquid chromatography with tandem mass spectrometry (LC-MS/MS). The in...
In vitro inhibition of human CYP2D6 by the chiral pesticide fipronil and its me...
Carrão, Daniel Blascke; Habenchus, Maísa Daniela; de Albuquerque, Nayara Cristina Perez; da Silva, Rodrigo Moreira; Lopes, Norberto PeporineMade available in DSpace on 2019-10-06T15:49:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fipronil is a chiral insecticide employed worldwide in crops, control of public hygiene and control of veterinary pests. Humans can be exposed to fipronil through occupational, food, and environmental contamination. Therefore, the risk asses...