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Altered renal response to acute volume expansion in transgenic rats harboring t...
Passaglio, Kátia Tomagnini; Baltatu, Ovidiu; Machado, Raquel do Pilar; Reis, Adelina Martha dos; Pesquero, João Bosco; Bader, MichaelThe renal response to acute volume expansion was investigated in transgenic (TGR) rats harboring the human tissue kallikrein gene. After a primer injection of 0.9% NaCl (3 ml/100 g, i.v), Sprague–Dawley (SD) or TGR rats received a continuous infusion of 0.9% NaCl (15 Al/ 100 g/min, i.a.) through a catheter placed into the carotid artery. Acute volume expansion was produced by a second injection of 0.9% NaCl (2 ...
Date: 2015
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Origin: Oasisbr