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CRISPR‑Cas9 engineered Saccharomyces cerevisiae for endolysin delivery to comba...

Sáez Moreno, David; Cunha, Joana; Melo, Luís Daniel Rodrigues; Tanaka, Kenya; Bamba, Takahiro; Hasunuma, Tomosiha; Azeredo, Joana; Domingues, Lucília

Listeriosis is an infection caused by the consumption of food contaminated with Listeria monocytogenes. It leads to febrile gastroenteritis, central nervous system infections, and even death in risk populations. Bacteriophage endolysins selectively kill bacteria hydrolyzing their cell walls and have emerged as a potential tool for listeriosis control. Ply511 is an anti-Listeria endolysin that has activity again...


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