11 documents found, page 1 of 2

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Overweight, Obesity, And Cardiovascular Disease In Heterozygous Familial Hyperc...

Elshorbagy, Amany; Vallejo-Vaz, Antonio J.; Barkas, Fotios; Lyons, Alexander R.M.; Stevens, Christophe A.T.; Dharmayat, Kanika I.; Catapano, Alberico L.

Background and aims: Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear. Methods: Cross-sectional analysis was conducted in 35 540 patients ...


Upfront lipid-lowering combination therapy in high cardiovascular risk patients...

Banach, Maciej; Surma, Stanisław; Guzik, Tomasz J.; Penson, Peter E.; Blaha, Michael J.; Pinto, Fausto J.; Sperling, Laurence S.

Despite three decades of using statin therapy, 20 years of experience with ezetimbe, and availability of innovative non-statin lipid lowering therapies (LLT), there are still about 70% patients over the low-density lipoprotein cholesterol (LDL-C) goal, with every 5th to 6th being over the target from the group of very high and extremely high cardiovascular disease (CVD) risk patients. Adding another even every ...


Global burden of chronic respiratory diseases and risk factors, 1990-2019: an u...

Momtazmanesh, Sara; Moghaddam, Sahar Saeedi; Ghamari, Seyyed-Hadi; Rad, Elaheh Malakan; Rezaei, Negar; Shobeiri, Parnian; Aali, Amirali

Background Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-communicable diseases by 2030. We provided global, regional, and national estimates of the burden of CRDs and their attributable risks from 1990 to 2019. Methods Using...


Global variation in diabetes diagnosis and prevalence based on fasting glucose ...

Zhou, Bin; Sheffer, Kate E.; Bennett, James E.; Gregg, Edward W.; Danaei, Goodarz; Singleton, Rosie K.; Shaw, Jonathan E.; Mishra, Anu

Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG,...


Heterogeneous contributions of change in population distribution of body mass i...

Iurilli, Maria L. C.; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, Honor

Made available in DSpace on 2022-04-28T19:30:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01; From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of ...

Date: 2022   |   Origin: Oasisbr

Worldwide trends in hypertension prevalence and progress in treatment and contr...

Zhou, Bin; Carrillo-Larco, Rodrigo M.; Danaei, Goodarz; Riley, Leanne M.; Paciorek, Christopher J.; Stevens, Gretchen A.; Gregg, Edward W.

Made available in DSpace on 2022-04-28T17:23:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-11; WHO; Abdul Latif Jameel Institute for Disease and Emergency Analytics - Community Jameel, at Imperial College London, London, UK; British Heart Foundation (Centre of Research Excellence); Background Hypertension can be detected at the primary health-care level and low-cost treatments can effectively con...

Date: 2022   |   Origin: Oasisbr

Heterogeneous contributions of change in population distribution of body mass i...

Iurilli, Maria L. C.; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, Honor

Made available in DSpace on 2021-06-25T15:08:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-09; Wellcome Trust; From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in th...

Date: 2021   |   Origin: Oasisbr

Worldwide trends in body-mass index, underweight, overweight, and obesity from ...

Ezzati, Majid; Bentham, James; Di Cesare, Mariachiara; Bilano, Ver; Bixby, Honor; Zhou, Bin; Stevens, Gretchen A.; Riley, Leanne M.; Taddei, Cristina

Made available in DSpace on 2018-11-26T20:04:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-16; Wellcome Trust; AstraZeneca; Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cove...

Date: 2018   |   Origin: Oasisbr

Contributions of mean and shape of blood pressure distribution to worldwide tre...

Zhou, Bin; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; Hajifathalian, Kaveh; Taddei, Cristina; Carrillo-Larco, Rodrigo M.

Made available in DSpace on 2018-11-26T22:38:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-01; Wellcome Trust; Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successfu...

Date: 2018   |   Origin: Oasisbr

Overview of the current status of familial hypercholesterolaemia care in over 6...

EAS Familial Hypercholesterolaemia Studies Collaboration; Vallejo-Vaz, Antonio J.; De Marco, Martina; Stevens, Christophe A.T.; Akram, Asif

Management of familial hypercholesterolaemia (FH) may vary across different settings due to factors related to population characteristics, practice, resources and/or policies. We conducted a survey among the worldwide network of EAS FHSC Lead Investigators to provide an overview of FH status in different countries.


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