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Evaluation of the antitumour and antiproliferative effect of xanthohumol-loaded...

Fonseca, M; Macedo, AS; Lima, SAC; Reis, S; Soares, R; Fonte, P

Cutaneous melanoma is the deadliest type of skin cancer and current treatment is still inadequate, with low patient survival rates. The polyphenol xanthohumol has been shown to inhibit tumourigenesis and metastasization, however its physicochemical properties restrict its application. In this work, we developed PLGA nanoparticles encapsulating xanthohumol and tested its antipro-liferative, antitumour, and migra...


Practice of spirometry among physicians caring for children with asthma in Port...

Constant, C; Cosme, J; Fernandes, RM; Fonte, P; Fonseca, JA; Alves, C; Bandeira, T

Date: 2020   |   Origin: Saúde - CUF

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