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Participação do propranolol no reparo tecidual de lesões isquêmicas cutâneas em...

Bandeira, Ana Carla Balthar

Submitted by Boris Flegr (boris@uerj.br) on 2021-01-05T18:13:07Z No. of bitstreams: 1 Dissertacao Ana Carla.pdf: 1462180 bytes, checksum: e31472e4f13faa54ff3416ee0af4d837 (MD5); Made available in DSpace on 2021-01-05T18:13:07Z (GMT). No. of bitstreams: 1 Dissertacao Ana Carla.pdf: 1462180 bytes, checksum: e31472e4f13faa54ff3416ee0af4d837 (MD5) Previous issue date: 2012-05-11; Coordenação de Aperfeiçoamento de P...

Date: 2021   |   Origin: Oasisbr

Exogenous surfactant prevents hyperoxiainduced lung injury in adult mice.

Bezerra, Frank Silva; Ramos, Camila de Oliveira; Castro, Thalles de Freitas; Araújo, Natália Pereira da Silva; Souza, Ana Beatriz Farias de

Background: In addition to the risk of developing ventilator-induced lung injury, patients with ARDS are at risk of developing hyperoxic injury due the supra-physiological oxygen supplementation clinically required to reverse hypoxemia. Alterations of endogenous surfactant system participate in the pulmonary dysfunction observed in ARDS. Administration of exogenous surfactant could have protective effects durin...

Date: 2020   |   Origin: Oasisbr

The exposure to formaldehyde causes renal dysfunction, inflammation and redox i...

Ramos, Camila de Oliveira; Nardeli, Clarissa Rodrigues; Campos, Keila Karine Duarte; Pena, Karina Braga; Machado, Dafne Fernandes

Twenty-eight Fischer male rats were divided into four groups: control group (CG), exposed to the ambient air, and groups exposed to formaldehyde (FA) at concentrations of 1% (FA1%), 5% (FA5%) and 10% (FA10%). Kidney function was assessed by dosage of uric acid, creatinine and urea. Morphometry was performed on the thickness of the lumen of Bowman's capsule and diameter of the lumen of the renal tubules. We eval...

Date: 2017   |   Origin: Oasisbr

The antioxidant and anti-inflammatory properties of lycopene in mice lungs expo...

Campos, Keila Karine Duarte; Araújo, Glaucy Rodrigues de; Martins, Thais Lourenço; Bandeira, Ana Carla Balthar; Costa, Guilherme de Paula

Lycopene is a carotenoid with knownantioxidant and anti-inflammatory properties.Weaimed to evaluate the in vitro and in vivo effects of lycopene on reducing the redox imbalance and inflammation induced by cigarette smoke (CS). For the in vitro study, J774A.1 (macrophages) cells were incubated in the presence of 0.5, 1.0, 2.0, 4.0, 8.0, 10.0 and 25 μMof lycopene for 3, 6 and 24 h or in the presence of 0.1%, 0.25...

Date: 2017   |   Origin: Oasisbr

Avaliação do efeito protetor do licopeno em um modelo de hepatotoxicidade induz...

Bandeira, Ana Carla Balthar

Programa de Pós-Graduação em Ciências Biológicas. Núcleo de Pesquisas em Ciências Biológicas, Pró-Reitoria de Pesquisa de Pós Graduação, Universidade Federal de Ouro Preto.; O uso do paracetamol (APAP), um fármaco com efeitos antipiréticos e analgésicos, é a principal causa de lesão hepática induzida por drogas. O modelo de lesão hepática induzida por APAP é um dos modelos mais populares para testar potenciais ...

Date: 2017   |   Origin: Oasisbr

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in C57BL...

Bandeira, Ana Carla Balthar; Silva, Rafaella Cecília da; Rossoni Júnior, Joamyr Victor; Figueiredo, Vivian Paulino; Silva, André Talvani Pedrosa da

Acetaminophen (APAP) is an antipyretic and analgesic drug that, in high doses, leads to severe liver injury and potentially death. Oxidative stress is an important event in APAP overdose. Researchers are looking for natural antioxidants with the potential to mitigate the harmful effects of reactive oxygen species in different models. Lycopene has been widely studied for its antioxidant properties. The aim of th...

Date: 2017   |   Origin: Oasisbr

The oxidative response of mouse hearts is modulated by genetic background.

Silva, Marco Aurélio dos Santos; Nagato, Akinori Cardozo; Trajano, Eduardo Tavares Lima; Alves, Jackson Nogueira; Bandeira, Ana Carla Balthar

Background: Smoking plays an important role in cardiovascular diseases. However, the reasons why some individuals develop those diseases and others do not remain to be explained. Objective: This study aimed at assessing the redox profile of the heart of different mouse strains after exposure to cigarette smoke. Methods: Male mice of the Swiss (n = 10), C3H (n = 10), BALB/c (n = 10) and C57BL/6 (n = 10) strains ...

Date: 2016   |   Origin: Oasisbr

Oxidative effects on lung inflammatory response in rats exposed to different co...

Murta, Giselle Luciane; Campos, Keila Karine Duarte; Bandeira, Ana Carla Balthar; Diniz, Mirla Fiuza; Costa, Guilherme de Paula; Costa, Daniela Caldeira

The formaldehyde (FA) is a crosslinking agent that reacts with cellular macromolecules such as proteins, nucleic acids and molecules with low molecular weight such as amino acids, and it has been linked to inflammatory processes and oxidative stress. This study aimed to analyze the oxidative effects on pulmonary inflammatory response in Fischer rats exposed to different concentrations of FA. Twenty-eight Fische...

Date: 2016   |   Origin: Oasisbr

Protótipo de ventilação mecânica espontânea e artificial.

Nagato, Akinori Cardozo; Diniz, Mirla Fiuza; Bandeira, Ana Carla Balthar; Bezerra, Frank Silva

A ventilação mecânica é utilizada como alternativa quando pacientes se encontram em quadros de insuficiência respiratória aguda ou crônica. O presente estudo teve como objetivo apresentar um protótipo que contribuirá para o ensino da ventilação mecânica espontânea e artificial nos cursos das áreas de saúde e biotecnológica. Materiais e Métodos: a pesquisa foi realizada no Laboratório de Biomorfologia e Patologi...

Date: 2015   |   Origin: Oasisbr

Prevalência do tabagismo entre discentes do curso de enfermagem da Universidade...

Bandeira, Ana Carla Balthar; Dornelas, Tereza Aparecida; Silva, Marco Aurélio dos Santos; Dornelas, Geovani Nunes; Rodrigues, Lília Marques Simões

O objetivo deste estudo foi levantar a prevalência e o perfil de tabagistas entre discentes do Curso de Enfermagem da Universidade Severino Sombra. Para isto, durante o período de fevereiro a março de 2009 foi aplicado um questionário para uma amostra de 200 alunos devidamente matriculados e com 18 anos completos. Foi utilizada a análise de prevalência, aproximada em 100%. A prevalência de fumantes, ex-fumantes...

Date: 2013   |   Origin: Oasisbr

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