45 documents found, page 1 of 5

RSV-Bacterial Co-Infection Is Associated With Increased Illness Severity in Hos...

During the autumn/winter respiratory syncytial virus (RSV) epidemics, bacterial co-infection is common and affects the disease severity. We aimed to understand the relationship between RSV-bacterial co-infections and clinical severity since the RSV seasonality change after COVID-19 pandemic. We conducted a prospective, sentinel surveillance study at 20 sites in Portugal in children under 2 years hospitalized wi...

Strategies to reduce the burden of respiratory syncytial virus infections in ch...

Strategies to Reduce the Burden of Respiratory Syncytial Virus Infections in Ch...

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Respiratory syncytial virus under 2 years of age: hospitalization trends and ri...

Introduction and Objectives: Respiratory Syncytial Virus (RSV) infection is an important cause of hospitalization in children under five years. A national RSV sentinel network was set up in Portugal in April 2021. We describe the trends in RSV hospitalizations until September 2022 and identify risk factors for severe disease. Methods: Acute respiratory infections in hospitalized children under two years were re...

Implementation of a Nationwide Surveillance Network of Respiratory Syncytial Vi...

Human respiratory syncytial virus (RSV) is associated with substantial morbidity and mortality in infants, young children and elderly. Monoclonal antibodies (MAb) therapy is the available method to prevent and combat severe disease in infants, nevertheless there is a global effort in the development of vaccines and new generation of MAb. In this sense, RSV surveillance is essential to estimate the burden of RSV...

Climate Interactions and Respiratory Diseases in Children

Introduction: Temperature and relative humidity affect health, particularly the respiratory system. Children represent a risk group, due to immature systems and continual development. The present study aimed to analyze the effects of temperature and relative humidity on hospitalizations of children due to asthma exacerbations and respiratory infections. Methods: This retrospective study analyzed administrative ...

Burden and severity of children's hospitalizations by respiratory syncytial vir...

Background: Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory infection (ALRI) in young children and is of considerable burden on healthcare systems. Our study aimed to evaluate ALRI hospitalizations related to RSV in children in Portugal. Methods: We reviewed hospitalizations potentially related to RSV in children aged <5 years from 2015 to 2018, using anonymized administrative da...

Bronchial Hypersecretion as a Clue for Asthma Diagnosis

Primary ciliary dyskinesia due to CCNO mutations : a genotype‐phenotype correla...

Primary ciliary dyskinesia (PCD) is genetically and clinically heterogeneous. CCNO mutations are associated with chronic destructive lung disease and were first described in 2014. Early reports suggest that CCNO is mutated more frequently than expected, however, these are considered rare. We report on three eleven-year-old children with PCD due to CCNO mutations. All children presented early-onset respiratory s...

Cardiovascular Compromise in Children with Neuromuscular Disease with Respirato...

Abstract Introduction: Neuromuscular diseases can be followed by cardiomyopathy and/or arrhythmias that have prognostic consequences. Although respiratory failure is the most frequent cause of death in this group of patients, heart disease is independent of ventilatory compromise and should be investigated. We aimed to investigate the cardiovascular follow-up and diagnosis of a population of patients with neuro...