15 documents found, page 1 of 2

Pantoprazole-Induced Liver Injury in the Setting of Diabetic Ketoacidosis

N/a.; N/a.

Drug-associated acute kidney disease: data from a world pharmacovigilance database

Background: Drugs are a frequent cause of nephrotoxicity, especially in the context of acute kidney disease (AKD), with a significant number of cases being drug-associated. The WHO's VigiBase is a powerful tool for identifying drugs described and associated with the development of AKD. Methods: We retrieved data from the period 1968 to 2022 regarding notifications of adverse drug reactions (ADR). The extracted ...

Drug-related glomerular phenotypes: a global pharmacovigilance perspective

Introduction: Adverse drug reactions are a significant problem in modern society, stemming from the increase in prescribed medications, over-the-counter drugs, and overall polypharmacy. Glomerular disorders are one of the frequently reported renal conditions associated with medication use. VigiBase is a significant tool for evaluating events associated with drug use, and, to the authors’ knowledge, no study has...

Drug‐Associated Nephrotic Syndrome: A Global Pharmacovigilance Perspective

Introduction: Nephrotic syndrome is a rare clinical manifestation, with an estimated incidence of 3 cases per 100 000 population per year, which can be triggered by medications contributing to the development of its histopathological forms. The literature references various drugs such as antibiotics, allopurinol, pamidronate, sirolimus, among others. Pharmacovigilance studies enable the evaluation of the safety...

Pantoprazole-induced liver injury in the setting of diabetic ketoacidosis

Critically ill patients are at higher risk of acquired liver in-jury, given the multiple coexisting potential causes of injury.1They are also at risk of stress ulcers, and prophylaxis with proton pump inhibitors (PPIs) is common in Intensive Care Units (ICUs). A 54-year-old woman was admitted to the ICU due to diabetic ketoacidosis (DKA). On admission, she was hemo-dynamically stable, with a Glasgow Coma Scale ...

Drug-associated acute kidney disease – data from a world pharmacovigilance data...

Background Drugs are a frequent cause of nephrotoxicity, especially in the context of acute kidney disease (AKD), with a significant number of cases being drug-associated. The WHO's VigiBase is a powerful tool for identifying drugs described and associated with the development of AKD. Methods We retrieved data from the period 1968 to 2022 regarding notifications of adverse drug reactions (ADR). The extracted me...

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Endovascular Treatment in Acute Ischemic Stroke: “Urgency in Reducing Asymmetries”

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Tratamento endovascular no acidente vascular cerebral isquémico: “Urgência na r...

Lemos com bastante satisfação o estudo de Dias et al1 publicado na Acta Médica Portuguesa que revelou as assimetrias nacionais no acesso ao tratamento endovascular (TEV) no acidente vascular cerebral (AVC) isquémico por oclusão de grande vaso proximal (OVP). Felizmente, no período em análise houve melhoria nacional das taxas de TEV, mais evidente nos distritos próximos de hospitais com TEV (HCTEV), tendo-se dem...

Incidence and case-fatality from spontaneous intracerebral hemorrhage in a sout...

Background: There is scarce information on incidence and case fatality of spontaneous intracerebral hemorrhage (SICH) in certain regions of the world, including in Europe. There is no community-based data on SICH in Southern Portugal. Aim: To determine the incidence and early case-fatality from SICH in Algarve, the southernmost region of Portugal. Methods: The recommended criteria for stroke incidence studies w...