Ideally, wastewater treatment aims to produce water indistinguishable from freshwater, especially for reuse. This study evaluated bacterial community and antibiotic resistance variations throughout treatment and benchmarked these with freshwater sources. Samples collected from six points of a full-scale wastewater treatment plant, pilot-scale advanced treatment options (non-thermal plasma - NTP, ultrafiltration...
Considerando a necessidade de utilizar águas residuais tratadas para irrigação agrícola, e a baixa aceitação pública desta prática, neste estudo pretendeu-se investigar a evolução da água residual ao longo do tratamento e comparar com fontes de água doce, no que se refere a comunidade bacteriana e perfis de resistência a antibióticos. As amostras foram colhidas em 6 pontos de uma estação de tratamento de água r...
Background/Objective: Individual health and organizational performance are strongly influenced by how people manage stress, or how they cope. Analysis and understanding of bidirectional association of BriefCOPE and COPSOQII and a unidirectional association of these two with “Índice de Capacidade para o Trabalho (ICT)”, a Portuguese version of Work Ability Index (WAI) in a health care professionals (e.g. Physici...
Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic that possesses potent activity against both Gram-positive and Gram-negative bacteria and is used to treat many infections. Despite its widespread use, ciprofloxacin is associated with side effects, which might be reduced by improving its pharmacokinetic properties. The chemical structure of ciprofloxacin is the source of some of its limitations, which...
Purpose: To investigate the subjective experience of adult cancer patients undergoing external radiotherapy and provide evidence for better practices in radiotherapy services. Methods: A systematic review was performed according to the PRISMA Statement Guidelines. Qualitative and mixed studies were identified through five electronic databases (CINAHL, PsychINFO, MEDLINE, Scopus, and Web of Science), between Mar...
Passou exatamente uma década sobre a criação do Arquivo de Memória, projeto intergeracional que nasceu com o apoio da Fundação Calouste Gulbenkian, assente na ideia de atenuar o isolamento dos mais velhos, valorizando as suas memórias, que são registadas pelos mais novos e disponibilizadas para todos através de um sistema de gestão da informação e de um sitio na internet (www.arquivodememoria.pt). O projeto deu...
Staphylococcal food poisoning is a disease that originates significant health and economic losses and is caused by Staphylococcus aureus strains able to produce enterotoxins. The aim of this work is to go further on the study of the volatile exometabolome of S. aureus using an advanced gas chromatographic technique. Enterotoxic and non-enterotoxic strains were assessed. The volatile exometabolome profile compri...
A Altran Portugal é atualmente um dos principais players na Consultoria de Inovação e Tecnológica em Portugal, estando presentes em vários setores de atividade como o Financeiro, Telecomunicações & Media, Administração Pública, Indústria, Energy & Life Sciences e Intelligent Systems e Utilities [1]. Com mais de 800 colaboradores, apresenta um modelo de negócio diferenciado, e a sua atividade tem uma estrutura a...
Intrinsic and acquired resistance to chemotherapy is the fundamental reason for treatment failure for many cancer patients. The identification of molecular mechanisms involved in drug resistance or sensitization is imperative. Here we report that tribbles homologue 2 (TRIB2) ablates forkhead box O activation and disrupts the p53/MDM2 regulatory axis, conferring resistance to various chemotherapeutics. TRIB2 sup...