6 documents found, page 1 of 1
Evaluation and Management of Nonculprit Lesions in STEMI
Thim, T; van der Hoeven, NW; Musto, C; Nijveldt, R; Götberg, M; Engstrøm, T; Smits, PC; Oldroyd, KG; Gershlick, AH; Escaned, J; Baptista, SB, et al.Nonculprit lesions are frequently observed in patients with ST-segment elevation myocardial infarction. Results from recent randomized clinical trials suggest that complete revascularization after ST-segment elevation myocardial infarction improves outcomes. In this state-of-the-art paper, the authors review these trials and consider how best to determine which nonculprit lesions require revascularization and w...
Instantaneous wave-free ratio cutoff values for nonculprit stenosis classificat...
Thim, T; Götberg, M; Fröbert, O; Nijveldt, R; van Royen, N; Baptista, SB, et al.OBJECTIVES: The instantaneous wave-free ratio cutoff value of <0.90 for hemodynamic significance of coronary stenoses has been validated in stable patients. We examined different cutoff values in the evaluation of nonculprit stenoses in patients with ST-segment elevation myocardial infarction. METHODS: We measured instantaneous wave-free ratio across nonculprit stenoses in the acute setting and at follow-up in ...
Comparison of Major Adverse Cardiac Events Between Instantaneous Wave-Free Rati...
Lee, J; Choi, K; Koo, B; Dehbi, H; Doh, J; Nam, C; Baptista, SB, et al.; The DEFINE-FLAIR Trial InvestigatorsIMPORTANCE: Invasive physiologic indices such as fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are used in clinical practice. Nevertheless, comparative prognostic outcomes of iFR-guided and FFR-guided treatment in patients with type 2 diabetes have not yet been fully investigated. OBJECTIVE: To compare 1-year clinical outcomes of iFR-guided or FFR-guided treatment in patients with and wi...
Clinical Events After Deferral of LAD Revascularization Following Physiological...
Sen, S; Ahmad, Y; Dehbi, H; Howard, J; Iglesias, J; Al-Lamee, R; Baptista, SB, et al.BACKGROUND: Physicians are not always comfortable deferring treatment of a stenosis in the left anterior descending (LAD) artery because of the perception that there is a high risk of major adverse cardiac events (MACE). The authors describe, using the DEFINE-FLAIR (Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation) trial, MACE rates when LAD lesions are deferred, guided by physio...
Sex Differences in Instantaneous Wave-Free Ratio or Fractional Flow Reserve-Gui...
Kim, C; Koo, B-K; Dehbi, H-M; Lee, J; Doh, J-H; Nam, C-W, et al.; Baptista, SB, et al.Objectives: This study sought to evaluate sex differences in procedural characteristics and clinical outcomes of instantaneous wave-free ratio (iFR)- and fractional flow reserve (FFR)-guided revascularization strategies. Background: An iFR-guided strategy has shown a lower revascularization rate than an FFR-guided strategy, without differences in clinical outcomes. Methods: This is a post hoc analysis of the DE...
Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI
Davies, J; Sen, S; Dehbi, M; Al-Lamee, R; Petraco, R; Nijjer SS1, S; Baptista, SB, et al.BACKGROUND: Coronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than revascularization guided by angiography alone. It is unknown whether the instantaneous wave-free ratio (iFR), an alternative measure that does not require the administration of adenosine, will offer benefits similar to those of FFR. METHODS: We randomly assigned 2492...