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Functional neutralization of HIV-1 Vif protein by intracellular immunization in...
Goncalves, J; Silva, F; Freitas-Vieira, A; Santa-Marta, M; Malho, R; Yang, X; Gabuzda, D; Barbas, CHuman immunodeficiency virus type 1 (HIV-1) encoded Vif protein is important for viral replication and infectivity. Therefore, Vif is considered to be an important alternative therapeutic target for inhibition of viral infectivity at the level of viral as
Functional neutralization of HIV-1 Vif protein by intracellular immunization in...
Goncalves, J; Silva, F; Freitas-Vieira, A; Santa-Marta, M; Malho, R; Yang, XY; Gabuzda, D; Barbas, CHuman immunodeficiency virus type 1 (HIV-1)-encoded Vif protein is important for viral replication and infectivity. Vif is a cytoplasmic protein that acts during virus assembly by an unknown mechanism, enhancing viral infectivity. The action of Vif in producer cells is essential for the completion of proviral DNA synthesis following virus entry. Therefore, Vif is considered to be an important alternative therap...