2 documents found, page 1 of 1
Identificação e caracterização da expressão gênica das proteínas Rad23 e Rad4, ...
Silva, Camila SiqueiraDNA is often damaged by environmental agents which lead to the up-regulation of several genes involved in different repair pathways. The regulation of DNA repair is important for cell survival following exposure to DNA-damaging agents. Schistosoma mansoni is a parasite that undergoes several modifications in its complex life cycle, being exposed to a subset of DNA-damaging agents, such as the environment and ho...
Schistosoma mansoni encodes SMT3B and SMT3C molecules responsible for post-tran...
Cabral, Fernanda Janku; Pereira Junior, Olavo dos Santos; Silva, Camila Siqueira; Cota, Renata Guerra de Sá; Rodrigues, VanderleiThe sumoylation pathway is a post-translational modification of nuclear proteins widespread among several organisms. SMT3C is the main protein involved in this process and it is covalently conjugated to a diverse assortment of nuclear protein targets. To date, 3 SUMO paralogues (SMT3C, A/B) have been characterized in mammals and plants. In this work we characterized two SUMO related genes, named SMT3B and SMT3C...