5 documents found, page 1 of 1
A multiparametric microbial and biochemical model for predicting postmortem int...
Teixeira, Maria J.; Barbosa, Daniel J.; Barbosa, Joana; Dinis-Oliveira, Ricardo Jorge; Freitas, Ana R.Background: Postmortem interval (PMI) estimation remains a major challenge in forensic science due to the influence of multiple factors. Traditional methods are often limited to early postmortem stages and lack precision in advanced decomposition [1,2]. Emerging approaches based on postmortem microbiology (thanatomicrobiome) and biochemical alterations (thanatochemistry) show promise [3,4], although their combi...
Bacterial load and dynamics: exploring their potential as biomarkers for postmo...
Teixeira, Maria J.; Barbosa, Daniel J.; Dinis-Oliveira, Ricardo Jorge; Freitas, Ana R.Background: Establishing the postmortem interval (PMI), the time since death, is vital in forensic investigations but remains challenging due to multiple factors like the cause of death, body location, and environmental conditions [1]. Traditional PMI estimation methods include Algor Mortis, Rigor Mortis, and Livor Mortis, along with complementary approaches from entomology, botany, and microbiology, though all...
ZYG-12/Hook's dual role as a dynein adaptor for early endosomes and nuclei is r...
Carvalho, Cátia; Moreira, Matilde; Barbosa, Daniel J.; Chan, Fung-Yi; Koehnen, Carlota Boal; Teixeira, Vanessa; Rocha, Helder; Green, MattieThe microtubule motor cytoplasmic dynein-1 transports and positions variousorganelles, but the molecular basis of this functional diversity is not fully understood. Cargoadaptors of the Hook protein family recruit dynein to early endosomes (EE) in fungi andhuman cells by forming the FTS–Hook–FHIP (FHF) complex. By contrast, the Caenorhabdi-tis elegans Hook homologue ZYG-12 recruits dynein to the nuclear envelop...
Mapping of key bacterial species for postmortem interval calculation
Cláudia-Ferreira, Ana; Barbosa, Daniel J.; Campos, Carla; Dinis-Oliveira, Ricardo Jorge; Freitas, Ana R.Background: Estimation of the Postmortem Interval (PMI), the time elapsed since death, is one of the most challenging issues in forensic sciences [1]. Most studies focus on extensive bacterial sequencing, but culture-based experiments for higher taxonomic resolution remain scarce [2]. Objective: We aimed to analyze total bacterial counts and map Enterococcus faecalis, Staphylococcus aureusand Escherichia coli i...
Mapping of key bacterial species for Postmorteminterval calculation
Ferreira, Ana Cláudia; Barbosa, Daniel J.; Campos, Carla; Oliveira, Ricardo Jorge Dinis; Freitas, Ana R.Estimation of the PostmortemInterval (PMI), the time elapsed since death, is one of the most challenging issues in forensic sciences. Most studies focus on extensive bacterial sequencing, but culture-based experiments for higher taxonomic resolution remain scarce. We aimed to analyze total bacterial counts and map Enterococcus faecalis, Staphylococcus aureusand Escherichia coliin different organs and timepoints...