Introduction: Bee venom (BV) allergy is one of the most common causes of severe anaphylaxis. Venom immunotherapy (VIT) is considered the most effective treatment, but systemic reactions may occur. This study aimed to characterize the sensitization profile by molecular components of patients with BV anaphylaxis under VIT and to evaluate whether systemic reactions during the build-up phase of VIT protocol are rel...
Introduction: Hospitalizations due to angioedema are important especially in debilitating or life-threatening situations. The aim of this study was to evaluate the frequency and etiology of angioedema without urticaria in hospital admissions.Material and Methods: The admissions between 2009 and 2013 in Centro Hospitalar Lisboa Norte with a diagnosis grouped under the ICD9 codes of angioedema were retrospectivel...
Blue dyes have been increasingly used for staging breast cancer and melanoma.1 Their administration in association with radioisotope-labelled albumin is with rates of identification of sentinel lymph nodes of 99%. Patent blue V (PBV) is a member of the triarylmethane family, which also includes isosulfan blue and methylene blue (MB). The former shares structural homology with PBV, which is responsible for some ...
Chronic urticaria (CU) is characterized by an evanescent, itchy wheal and flare reaction that does not resolve completely after 6 weeks. It is a relatively frequent disease that causes significant morbidity. Its therapy with drugs other than H1-antihistamines has not yet been exhaustively studied, but recently some promising treatment options have been described. We describe a case of severe, corticosteroid-dep...
Local anesthetics (LA) are frequently used in medical and surgical and dental procedures. Adverse reactions to LA are rare, and hypersensitivity reactions are very rare. Nevertheless, they are the third more frequent cause of referral to Allergy Clinics due to drug allergy, after betalactamic antibiotics and non-steroidal anti-inflammatory agents. In this paper we review hypersensitivity reactions to LA and pro...