5 documents found, page 1 of 1
In vivo hydrogen peroxide diffusivity in brain tissue supports volume signaling...
Ledo, A.; Fernandes, E.; Salvador, A.; Laranjinha, J.; Barbosa, R. M.Hydrogen peroxide is a major redox signaling molecule underlying a novel paradigm of cell function and communication. A role for H2O2 as an intercellular signaling molecule and neuromodulator in the brain has become increasingly apparent, with evidence showing this biological oxidant to regulate neuronal polarity, connectivity, synaptic transmission and tuning of neuronal networks. This notion is supported by i...
Lipid nanomaterials for targeted delivery of dermocosmetic ingredients: advance...
Souto, Eliana B.; Jäger, E.; Jäger, A.; tepánek, P.; Cano, A.; Viseras, C.; Barbosa, R. M.; Chorilli, M.; Zielinska, A.; Severino, P.; Naveros, B. C.Despite the health benefits of the sun, overexposure to solar radiation without proper precautions can cause irreversible damage to exposed skin. In the search for balance between the risks and benefits of exposure to solar radiation in human health, a technological alternative was found, the incorporation of photoprotective products in lipid nanoparticulate systems for topical application. These nanometric sys...
Corrigendum to "European contribution to the study of ROS: A summary of the fin...
Egea, J; Fabregat, I; Frapart, Y M; Ghezzi, P; Görlach, A; Kietzmann, T; Kubaichuk, K; Knaus, U G; Lopez, M G; Olaso-Gonzalez, G; Petry, A; Schulz, RThis article/publication is based upon work from COST Action BM1203 (EU-ROS), supported by COST (European Cooperation in Science and Technology) which is funded by the Horizon 2020 Framework Programme of the European Union. COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scienti...
In vivo toxicity of enoxaparin encapsulated in mucoadhesive nanoparticles: topi...
Barbosa, R. M.
Human colon adenocarcinoma HT-29 cell: electrochemistry and nicotine stimulation
Oliveira, S. C. B.; Santarino, I. B.; Enache, T. A.; Nunes, C.; Laranjinha, J.; Barbosa, R. M.; Brett, A. M. OliveiraRecently, it was demonstrated that colorectal cancer HT-29 cells can secrete epinephrine (adrenaline) in an autocrine manner to auto-stimulate cellular growth by adrenoreceptors activation, and that this secretion is enhanced by nicotine, showing an indirect relation between colorectal cancer and tobacco. The electrochemical behaviour of human colon adenocarcinoma HT-29 cells from a colorectal adenocarcinoma ce...