3 documents found, page 1 of 1
Association of Oxelytrum cayennense (Silphidae,Coleoptera) with pig carcasses (...
Ururahy-Rodrigues, Alexandre; Rafael, José Albertino; Pujol-luz, Jose Roberto; Henriques, Augusto Loureiro; Queiroz, Margareth M.C.; Barbosa, R. R.
Monocyte activation is a feature of common variable immunodeficiency irrespecti...
Barbosa, R. R.; Silva, S. P.; Silva, S. L.; Tendeiro, R.; Melo, A. C.; Pedro, E.; Barbosa, M. P.; Santos, M. C.; Victorino, R. M.; Sousa, A. E.Common variable immunodeficiency disorders (CVID), the most frequent cause of symptomatic primary immunodeficiency, are defined by impaired antibody production. Notwithstanding, T cell activation and granulomatous manifestations represent the main causes of CVID morbidity even in patients receiving immunoglobulin (Ig) G replacement therapy. Additionally, gut pathology is a frequent feature of CVID. In this stud...
Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-c...
Barbosa, R. R.; Silva, S. P.; Silva, S. L.; Melo, A. C.; Pedro, E.; Barbosa, M. P.; Pereira-Santos, M. C.; Victorino, R. M.; Sousa, A. E.IL-17 is a pro-inflammatory cytokine implicated in autoimmune and inflammatory conditions. The development/survival of IL-17-producing CD4 T cells (Th17) share critical cues with B-cell differentiation and the circulating follicular T helper subset was recently shown to be enriched in Th17 cells able to help B-cell differentiation. We investigated a putative link between Th17-cell homeostasis and B cells by stu...