12 documents found, page 1 of 2
Tumor carcinoide brônquico como causa de pneumonia recorrente
Gomes Moreira, Ana Rita; Carvalho, Catarina; Silva, Gisela; Silva, Sílvia; Paupério, Gonçalo; Carvalho, Fátima; Barbosa, TelmaOs tumores neuroendócrinos (TNEs) são as neoplasias pulmonares primárias mais comuns. O diagnóstico pode ser desafiante, pois as manifestações clínicas são geralmente subtis e as alterações imagiológicas inespecíficas. Apesar da sua natureza indolente, os TNEs têm potencial metastático e podem causar morbilidade significativa. O diagnóstico precoce é fundamental para uma abordagem otimizada, uma vez que a resse...
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multic...
Pirnay, Jean-Paul; Djebara, Sarah; Steurs, Griet; Griselain, Johann; Cochez, Christel; De Soir, Steven; Glonti, Tea; Spiessens, An; Vanden Berghe, EmilyIn contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the first 100 consecutive cases of personalized BT of difficult-to-treat infections facilitated by a Belgian consortium i...
Bronchial carcinoid tumor as a cause of recurrent pneumonia
Gomes, Rita; Carvalho, Catarina; Silva, Gisela; Silva, Sílvia Ferreira; Paupério, Gonçalo S; Carvalho, Fátima; Barbosa, TelmaNeuroendocrine tumors (NETs) are the most common primary lung neoplasms. Clinical manifestations can be subtle, and chest radiograph usually shows non-specific findings, often leading to delayed or inaccurate diagnosis. Despite their indolent nature, NETs have metastatic potential and can cause significant morbidity. Early diagnosis is critical for optimal management, as surgical resection can be curative. The ...
Domiciliary High-Flow Nasal Therapy in Primary Ciliary Dyskinesia
Gomes, Rita; Queirós, Joana; Borges, Joana; Cardoso, Ana Lúcia; Barbosa, TelmaWe report the case of an adolescent with severe primary ciliary dyskinesia (PCD) phenotype associated with a rare genotype. His clinical condition deteriorated, with daily cough and breathlessness, hypoxemia, and lung function decline. Despite being started on home noninvasive ventilation (NIV), the symptoms progressed to dyspnea at rest and thoracic pain. High-flow nasal cannula (HFNC) was started during the d...
Pediatric hospitalizations due to SARS-CoV-2 infection with respiratory involve...
Monteiro, Sara; Lima, Joana; Barbosa, Telma; Morais, Lurdes; Reis, Maria Guilhermina; Ferreira-Magalhães, Manuel; Ramos, AnaIntroduction: SARS-CoV-2 may have several clinical presentations infection in children, with some requiring hospitalization. The published evidence is still scarce regarding the best approach and treatment for these cases. Objective: To describe pediatric hospitalizations due to SARS-CoV-2 respiratory infection in a tertiary centre. Material and methods: Retrospective observational study of SARS-CoV-2 admission...
Chromosome Instability in Asthma an Antioxidant Treatment as a Possible Pharmac...
Oliveira, Claúdia; Nogueira, Maria; Barbosa, Telma; Cardoso, Carmen; Neves, João; Costa, Solange; Porto, BeatrizAsthma is a disease with multiple phenotypes and different degrees of severity. Severe inflammation appears when oxidative stress (OS) overwhelms the antioxidant defense. Knowing the role of OS in the increase of chromosome instability (CI) and, consequently, in cancer predisposition, it is important to carry out studies to establish limits for OS harmful effects. The aim of this study was to evaluate OS-relate...
Assessment of asthmatic child inhalation device technique
Pinto, Pedro Tiago; Jeri, Miguel; Barbosa, TelmaIntroduction: In Portugal, asthma is a very common disease, particularly in pediatric age, and many children are treated with medications delivered by inhalation devices. It is known that child inhaler technique is often throughout the world. Aim: The aim of this paper is to describe the performance of asthmatic child device technique in a Portuguese children hospital in the city of Porto, (Centro Materno-Infan...
Cystic Fibrosis Newborn Screening in Portugal: PAP Value in Populations with St...
Marcão, Ana; Barreto, Celeste; Pereira, Luísa; Vaz, Luísa; Cavaco, José; Casimiro, Ana; Félix, Miguel; Silva, Teresa; Barbosa, Telma; Freitas, CristinaNewborn screening (NBS) for cystic fibrosis (CF) has been shown to be advantageous for children with CF, and has thus been included in most NBS programs using various algorithms. With this study, we intend to establish the most appropriate algorithm for CF-NBS in the Portuguese population, to determine the incidence, and to contribute to elucidating the genetic epidemiology of CF in Portugal. This was a nationw...
Assessment of asthmatic child inhalation device technique
Pinto, Pedro Tiago; Jeri, Miguel; Barbosa, TelmaIntroduction: In Portugal, asthma is a very common disease, particularly in pediatric age, and many children are treated with medications delivered by inhalation devices. It is known that child inhaler technique is often throughout the world. Aim: The aim of this paper is to describe the performance of asthmatic child device technique in a Portuguese children hospital in the city of Porto, (Centro Materno-Infan...
Caso radiológico
Freitas, Ana Cristina; Barbosa, Telma; Macedo, FilipeCriança de seis anos do sexo masculino, com radiograÞ a do tórax realizada no Serviço de Urgência, em contexto de infeção respiratória. Observou-se uma fina opacidade linear vertical que termina numa pequena opacidade arredondada, projetada no campo superior do hemitórax direito (Figura 1).; We present a case of a 6-year-old child in whom a chest x-ray is performed for a respiratory infection. An inverted comma...