The aim of this study was to examine the effects of (-)-myrtenol alone and combined with antifungal agents against Candida spp. The Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration of (-)-myrtenol and fluconazole against C. albicans and C. parapsilosis strains was obtained using CLSI guidelines. Combination of (-)-myrtenol with antifungal drugs was determined by checkboard test. The (...
Diabetes Mellitus (DM) is a metabolic syndrome characterized by hyperglycemia. Chronic complications affect a number of organs, including the lungs. Cissampelos sympodialis Eichl (Menispermaceae) is a plant used to treat respiratory diseases. The aim of this study was to evaluate the effect of Cissampelos sympodialis extract (CSE) in lungs of diabetic rats. We used 30 Wistar rats divided into three groups: cont...
CNPq, CAPES, PRONEX e FAPESB.; Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / UNEB. Departamento Ciências da Vida. Salvador, BA, Brasil; Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil; Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / UNEB. Departamento Ciências da Vida. Salvador, BA, Brasil; Fundação Oswaldo Cruz. ...
Texto completo: acesso restrito. p. 1557–1563; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-24T13:35:27Z No. of bitstreams: 1 10.1002ptr.4902.pdf: 237804 bytes, checksum: 8fb1facba729d829d7e76b35d51b82f5 (MD5); Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-09-08T20:27:16Z (GMT) No. of bitstreams: 1 10.1002ptr.4902.pdf: 237804 bytes, checksum: 8fb1facba729d829d7e7...
This study aimed to study the in vitro antioxidant activity and cytotoxicity on tumor cells lines of six synthetic substances derived from riparins. All the substances showed antioxidant activity and riparins C, D, E, F presented cell growth inhibition rates greater than 70%, suggesting that these molecules have antitumor properties. These substances also caused greater than 80% releases of cytoplasmic lactate ...
Riparin II (RipII), an alkamide isolated from the green fruit of Aniba riparia, was tested in the various animal models of inflammation to investigate its anti-inflammatory activity. Male Wistar rats (180–240 g) were treated with RipII by gavage at doses 25 or 50 mg/kg, before initiating the inflammatory responses. The tests used were paw edema induced by carrageenan, dextran, histamine or serotonin; peritoniti...
Universidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade Federal de São Carlos. Departamento de Química. São Carlos, SP, Brasil; Universidade de São Paulo. Instituto de Física de São Carlos. São Carlos, ...
The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4Hbenzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel condensation with benzaldehydes. The configurations and conformations of benzylidene benzothiazine derivatives were ...