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Epigenetic Analysis of Long-term Epilepsy-Associated Tumors by Methylation-Spec...

Jesus-Ribeiro, Joana; Ribeiro, Ilda Patrícia; Pires, Luis Miguel; Rebelo, Olinda; Pereira, Ricardo; Bento, Conceição; Sales, Francisco; Santana, Isabel

Introduction: Ganglioglioma and dysembryoplastic neuroepithelial tumor represent the most common neoplasms in the group of long-term epilepsy-associated tumors. Mapping of epigenetic alterations, particularly DNA methylation, has recently been shown to offer promising perspectives in brain tumors, identifying key genes that may serve as potential diagnostic biomarkers. We aim to perform a genetic and epigenetic...

Date: 2024   |   Origin: SINAPSE

Resective Epilepsy Surgery and Respective Histopathological Diagnoses: A Retros...

Jesus-Ribeiro, Joana; Rebelo, Olinda; Bento, Conceição; Pereira, Cristina; Robalo, Conceição; Rito, Manuel; Pereira, Ricardo; Costa, José Augusto

Introduction: Over recent decades, brain resection for drug-resistant epilepsy has proven to be a valuable treatment option. The histopathological classification was of paramount value for patient management. The aims of this study were to characterize our resective epilepsy surgical series including the histopathological diagnoses and to understand the differences in clinical practice between two different per...

Date: 2022   |   Origin: Acta Médica Portuguesa

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