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A recent shift from polygyny to monogamy in humans is suggested by the analysis...

Dupanloup, I; Pereira, L; Bertorelle, G; Calafell, F; Prata, MJ; Amorim, A; Barbujani, G

Molecular genetic data contain information on the history of populations. Evidence of prehistoric demographic expansions has been detected in the mitochondrial diversity of most human populations and in a Y-chromosome STR analysis, but not in a previous study of 11 Y-chromosome SNPs in Europeans. In this paper, we show that mismatch distributions and tests of mutation/drift equilibrium based on up to 166 Y-chro...


Y-chromosome mismatch distributions in Europe

Pereira, L; Dupanloup, I; Rosser, ZH; Jobling, MA; Barbujani, G

Ancient demographic events can be inferred from the distribution of pairwise sequence differences (or mismatches) among individuals. We analyzed a database of 3,677 Y chromosomes typed for 11 biallelic markers in 48 human populations from Europe and the Mediterranean area. Contrary to what is observed in the analysis of mitochondrial polymorphisms, Tajima's test was insignificant for most Y-chromosome samples, ...


Y-chromosomal diversity in Europe is clinal and influenced primarily by geograp...

Rosser, ZH; Zerjal, T; Hurles, ME; Adojaan, MA; Alavantic, D; Amorim, A; Amos, W; Armenteros, M; Arroyo, E; Barbujani, G; Beckman, L; Bertranpetit, J

Clinal patterns of autosomal genetic diversity within Europe have been interpreted in previous studies in terms of a Neolithic demic diffusion model for the spread of agriculture; in contrast, studies using mtDNA have traced many founding lineages to the Paleolithic and have not shown strongly clinal variation. We have used 11 human Y-chromosomal biallelic polymorphisms, defining 10 haplogroups, to analyze a sa...


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