2 documents found, page 1 of 1
Platelet antibody detection by flow cytometry: an effective method to evaluate ...
Bub,Carolina Bonet; Martinelli,Beatriz Moraes; Avelino,Thayna Mendonca; Goncalez,Ana Claudia; Barjas-Castro,Maria de Lourdes; Castro,VagnerBACKGROUND: Immune platelet refractoriness is mainly caused by human leukocyte antigen antibodies (80-90% of cases) and, to a lesser extent, by human platelet antigen antibodies. Refractoriness can be diagnosed by laboratory tests and patients should receive compatible platelet transfusions. A fast, effective and low cost antibody-screening method which detects platelet human leukocyte/platelet antigen antibodi...
Electrical properties of the red blood cell membrane and immunohematological in...
Fernandes,Heloise Pöckel; Cesar,Carlos Lenz; Barjas-Castro,Maria de LourdesHemagglutination is widely used in transfusion medicine and depends on several factors including antigens, antibodies, electrical properties of red blood cells and the environment of the reaction. Intermolecular forces are involved in agglutination with cell clumping occurring when the aggregation force is greater than the force of repulsion. Repulsive force is generated by negative charges on the red blood cel...