7 documents found, page 1 of 1
DNA methyltransferase expression (DNMT1, DNMT3a, and DNMT3b) as a potential bio...
Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Nascimento, João; Rosa, Paulo Caldeira; Henriques, José; Barrão, Sandra; Sadio, Silvia; Quendera, BrunoBackground/Objectives: Age-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (DNMT1, DNMT3A, and DNMT3B) in AMD patients and explore divergent expression patterns across different stages of AMD. Methods: Thirty-eight AMD patients were prospe...
DNA Methyltransferase Expression (DNMT1, DNMT3a, and DNMT3b) as a Potential Bio...
Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Nascimento, João; Caldeira Rosa, Paulo; Henriques, José; Barrão, Sandra; Sadio, Silvia; Quendera, BrunoAge-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (, , and ) in AMD patients and explore divergent expression patterns across different stages of AMD. : Thirty-eight AMD patients were prospectively enrolled and stratified by disease seve...
COVID-19 impact in a public ophthalmology service – Report 1
Camacho, Pedro; Salgueiro, L.; Barrão, Sandra; Brito, RicardoThe COVID-19 pandemic forced a concerted response from health services to lead to a reduction in care activity. It is a strategy to respond to this health problem centered on clinical provision and, simultaneously, on the protection of the community and health professionals. However, the direct and indirect impact on eye care is still unclear. Objective: To characterize the impact of COVID-19 in the complementa...
Anterior segment swept-source OCT in the post-operatory evaluation of patients ...
Rodrigues, Catarina; Cabral, Diogo; Camacho, Pedro; Pereira, Telmo; Santos, Cristina; Seldon, Raquel; Braz, Filipe; Barrão, Sandra; Varandas, GabrielaPurpose: Evaluate the Anterior Segment Swept-source Optical Coherence Tomography (AS-OCT) imaging features of medial rectus with previous surgery and to study the association of this features with the surgical plan. Methods: Evaluation of 43 control eyes (Group A) and 25 eyes submitted to medial rectus surgery (Group B). AS-OCT scans were obtained on lateral gaze at a fixation light. Muscle insertion(MI) was d...
COVID-19 impact in a public ophthalmology service – report 1
Camacho, Pedro; Salgueiro, L.; Barrão, Sandra; Brito, RicardoABSTRACT - The COVID-19 pandemic forced a concerted response from health services to lead to a reduction in care activity. It is a strategy to respond to this health problem centered on clinical provision and, simultaneously, on the protection of the community and health professionals. However, the direct and indirect impact on eye care is still unclear. Objective: To characterize the impact of COVID-19 in the ...
O diagnóstico da DMI precoce e intermédia: quais os achados no OCT e no OCTA
Barrão, Sandra; Medeiros, Marco Dutra; Camacho, PedroA degenerescência macular da idade (DMI) é uma das principais causas de cegueira irreversível. Sendo a magnitude da DMI acentuada pelo envelhecimento da população mundial, o que a reveste de um particular interesse em saúde pública, é importante poder-se separar e compreender as alterações iniciais da doença, ao nível das camadas mais externas da neuroretina incluindo os fotorreceptores, o epitélio pigmentar re...
Bull ́s Eye Maculopathy in a patient treated with efavirenz
Vaz Pereira, Cristina; Franco, Mónica; Guerra Pinto, Rita; Barrão, Sandra; Prior Filipe, HelenaObjective: To report a case of retinal toxicity associated with efavirenz in an adult. Methods: We describe a case of gradual-onset blurry vision in both eyes in a 37-year-old HIV caucasian woman, on antiretroviral therapy (ART), including efavirenz. Results: The patient presented with a best corrected visual acuity of 20/100 for the right eye (RE) and 20/125 for the left eye (LE). Fundoscopy revealed mottled a...