5 documents found, page 1 of 1
Factors Associated with Acute Kidney Injury in Community-Acquired Pneumonia: De...
Teles, Carolina; Magalhães, Ana; Dias da Costa, Tiago; Barra, Cátia; Silva, Ana Luísa; Albuquerque, Fernando; Gaspar, Elsa; Santos, LèlitaIntroduction: Acute kidney injury (AKI) is a frequent complication of community-acquired pneumonia (CAP). Nonetheless, the underlying pathophysiology is not fully understood. Certain factors have shown association with increased risk, but there is still data lacking. The main objective of this study was to identify factors associated with AKI in CAP. Methods: We conducted a retrospective study in patients with ...
Exposure to Obesogenic Environments during Perinatal Development Modulates Offs...
Sousa, Diana; Sá-Rocha, Mariana; Amaro, Andreia; Ferreira-Junior, Marcos Divino; Cavalcante, Keilah Valéria Naves; Monteiro-Alfredo, TamaehObesogenic environments such as Westernized diets, overnutrition, and exposure to glycation during gestation and lactation can alter peripheral neuroendocrine factors in offspring, predisposing for metabolic diseases in adulthood. Thus, we hypothesized that exposure to obesogenic environments during the perinatal period reprograms offspring energy balance mechanisms. Four rat obesogenic models were studied: mat...
Postnatal Overfeeding in Rodents Induces a Neurodevelopment Delay and Anxious-l...
Amaro, Andreia; Sousa, Diana Isabel Teixeira de; Sá-Rocha, Mariana; Ferreira-Junior, Marcos Divino; Rosendo-Silva, DanielaNutritional disturbances during the early postnatal period can have long-lasting effects on neurodevelopment and may be related to behavioural changes at adulthood. While such neuronal connection disruption can contribute to social and behaviour alterations, the dysregulation of the neuroendocrine pathways involved in nutrient-sensing balance may also cause such impairments, although the underlying mechanisms a...
Distinct Impact of Natural Sugars from Fruit Juices and Added Sugars on Caloric...
Monteiro-Alfredo, Tamaeh; Caramelo, Beatriz; Arbeláez, Daniela; Amaro, Andreia; Barra, Cátia; Silva, Daniela; Oliveira, Sara; Seiça, RaquelAlthough fruit juices are a natural source of sugars, there is a controversy whether their sugar content has similar harmful effects as beverages' added-sugars. We aimed to study the role of fruit juice sugars in inducing overweight, hyperglycaemia, glycation and oxidative stress in normal and diabetic animal models. In diabetic Goto-Kakizaki (GK) rats, we compared the effects of four different fruit juices (4-...
Variations in salivary function in a rodent model of pre-diabetes
Rodrigues, Lénia; Mouta, Raquel; Barra, Cátia; Costa, Ana R; Silva, Fernando C; Lopes, Orlando; Lima, Mónica; Lamy, ElsaDiabetes is a widespread disease representing an enormous part of the total health costs. An early diagnostic could be of extremely importance both for the understanding and prevention of this pathology. Saliva is a fluid with increasing interest as a source of biomarkers for disease diagnostic and saliva protein composition changes have already been reported for diabetic individuals. However, the studies were ...