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Do cognitive subtypes exist in people at clinical high risk for psychosis? Resu...

EU-GEI High Risk Study; Gifford, George; Avila, Alessia; Kempton, Matthew J.; Fusar-Poli, Paolo; Mccutcheon, Robert A.; Coutts, Fiona; Tognin, Stefania

Background and Hypothesis: Cognition has been associated with socio-occupational functioning in individuals at Clinical High Risk for Psychosis (CHR-P). The present study hypothesized that clustering CHR-P participants based on cognitive data could reveal clinically meaningful subtypes. Study Design: A cohort of 291 CHR-P subjects was recruited through the multicentre EU-GEI high-risk study. We explored whether...


Genetic susceptibility to the environment moderates the impact of childhood exp...

Barrantes-Vidal, Neus; Torrecilla, Pilar; Mas-Bermejo, Patricia; Papiol, Sergi; Bakermans-Kranenburg, Marian J.; Kwapil, Thomas R.; Rosa, Araceli

Background and Hypothesis: Consistent with diathesisstress models, psychosis research has focused on genetic moderation of adverse environmental exposures. In contrast, the Differential Susceptibility (DS) model suggests that the same genetic variants that increase risk-inducing effects of adverse experiences also enhance beneficial effects from positive experiences. This study examined whether individuals with...


Genetic differences in reactivity to the environment impact psychotic-like and ...

Barrantes-Vidal, Neus; Torrecilla, Pilar; Mas-Bermejo, Patricia; Papiol, Sergi; Bakermans-Kranenburg, Marian J.; Rosa, Araceli; Kwapi, Thomas R.

Background and Hypothesis: Consistent with diathesisstress models, psychosis research has focused on genetic moderation of adverse environmental exposures. In contrast, the Differential Susceptibility (DS) model suggests that the same genetic variants that increase risk-inducing effects of adverse experiences also enhance benefcial effects from positive experiences. This study examined whether individuals with ...


Attachment goes to court: child protection and custody issues

Forslund, Tommie; Granqvist, Pehr; Van IJzendoorn, Marinus; Sagi-Schwartz, Avi; Glaser, Danya; Steele, Miriam; Hammarlund, Mårten; Schuengel, Carlo

Attachment theory and research are drawn upon in many applied settings, including family courts, but misunderstandings are widespread and sometimes result in misapplications. The aim of this consensus statement is, therefore, to enhance understanding, counter misinformation, and steer family-court utilisation of attachment theory in a supportive, evidence-based direction, especially with regard to child protect...


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