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Overdiagnosis of lung cancer with low-dose computed tomography screening

Brodersen, John; Voss, Theis; Martiny, Frederik; Siersma, Volkert; Barratt, Alexandra; Heleno, Bruno

In low-dose computed tomography (LDCT) screening for lung cancer, all three main conditions for overdiagnosis in cancer screening are present: 1) a reservoir of slowly or nongrowing lung cancer exists; 2) LDCT is a high-resolution imaging technology with the potential to identify this reservoir; and 3) eligible screening participants have a high risk of dying from causes other than lung cancer. The degree of ov...


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