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How to get the most out of the ERS International Congress 2021 and an overview ...
Farr, Amy; Ubags, Niki; Brightling, Christopher; Miravitlles, Marc; Barrecheguren, Miriam; Laveneziana, Pierantonio; Gosens, Reinoud; Costello, RichardThe annual European Respiratory Society (ERS) International Congress will take place in a virtual format, from 5 to 8 September 2021. As in previous years, the programme will be full of outstanding scientific sessions in the field of respiratory medicine and enriching opportunities for Early Career Members (ECMs). In this article, we provide an overview of the structure and content of the Congress, as well as t...
Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Def...
Hamesch, Karim; Mandorfer, Mattias; Pereira, Vítor Magno; Moeller, Linda S.; Pons, Monica; Dolman, Grace E.; Reichert, Matthias C.BACKGROUND & AIMS: Alpha-1 antitrypsin deficiency (AATD) is among the most common genetic disorders. Severe AATD is caused by a homozygous mutation in the SERPINA1 gene that encodes the Glu342Lys substitution (called the Pi*Z mutation, Pi*ZZ genotype). Pi*ZZ carriers may develop lung and liver diseases. Mutation- associated lung disorders have been well studied, but less is known about the effects in liver. We ...