3 documents found, page 1 of 1
Tryptase in acute appendicitis: unveiling allergic connections through compelli...
Carvalho, Nuno; Carolino, Elisabete; Ferreira, Margarida; Coelho, Hélder; Santos, Catarina Rolo; Barreira, Ana Lúcia; Henriques, Susana; Cardoso, CarlosThe aetiology of acute appendicitis (AA), the most frequent abdominal surgical emergency, is still unclarified. Recent epidemiologic, clinical, and laboratory data point to an allergic component in the pathophysiology of AA. Mastocytes participate in the Th2 immune response, releasing inflammatory mediators from their granules upon stimulation by IgE-specific antigens. Among the well-known mediators are histami...
Eosinophil granule proteins involvement in acute appendicitis: an allergic dise...
Carvalho, Nuno; Carolino, Elisabete; Coelho, Hélder; Barreira, Ana Lúcia; Moreira, Luísa; André, Margarida; Henriques, Susana; Cardoso, CarlosSeveral pieces of evidence point to an allergic component as a trigger of acute appendicitis. As the Th2 immune response is characterized by eosinophil mobilization to the target organ and release of their cationic granule proteins, it is reasonable to investigate if the degranulation of eosinophils could be associated with the local injury. The primary aim of this study is to evaluate the participation of eosi...
SARCOPENIA IN GASTRIC CANCER AND BODY COMPOSITION CHANGES AFTER GASTRECTOMY
Ferreira, Margarida; Barreira, Ana Lúcia; Sardinha, Francisco; Costa, João; Rodrigues, Jéssica; Gonçalves, Afonso; Matos Costa, PauloSarcopenia is the phenomenon of loss of muscle strength, muscle performance and muscle mass due to either age (primary sarcopenia) or other illnesses such as cancer (secondary sarcopenia). Sarcopenia has often been defined in the literature as low muscle mass. Sarcopenia among gastric cancer patients has been shown to carry a higher risk of post-operative complications and a higher overall and disease-specific ...