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Effect of co-administration of BRL-37344 and tadalafil on reduction of overacti...

Carvalho, Marcos Fiuza de; Pamplona, Thuliermes Lopes; Barreira, Márcio Alencar; Fechine, Francisco Vagnaldo Jamacuru; Gonzaga-Silva, Lúcio Flávio

Purpose: To evaluate the impact of the combination of BRL 37344 and tadalafil (TDF) on the reduction of overactive bladder (OB) symptoms. Methods: Thirty mice were randomized into 5 groups (G) of 6 animals each. L-NAME was used to induce DO. G1: Control; G2: L-NAME; G3: L-NAME + TDF; G4: L-NAME + BRL 37344; G5: L-NAME + TDF + BRL 37344. After 30 days of treatment, the animals were submitted to cystometry to eva...

Date: 2019   |   Origin: Oasisbr

Liver transplantation in hepatitis delta : South America experience

Lima, Daniel Souza; Murad Júnior, Abdon José; Barreira, Márcio Alencar; Fernandes, Guilherme Cardoso; Coelho, Gustavo Rego; Garcia, José Huygens Parente

BACKGROUND: The Amazon region is one of the main endemic areas of hepatitis delta in the world and the only one related to the presence of genotype 3 of the delta virus. OBJECTIVE: To analyze the profile, mortality and survival of cirrhotic patients submitted to liver transplantation for chronic hepatitis delta virus and compare with those transplanted by hepatitis B virus monoinfection. METHODS: Retrospective,...

Date: 2018   |   Origin: Oasisbr

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