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Nanostructured lipid carriers loaded with cannabidiol: A novel antibiofilm appr...

Cunha, Joana; Barreira, Sérgio; Ferraz, Maria; Catita, José; Lúcio, Marlene; Carla Lopes

Introduction: Staphylococcus aureus and Staphylococcus epidermidis are major contributors to skin dysbiosis and infections, e.g. folliculitis and intravascular catheter infections, forming biofilms that enhance their resistance to antibiotics and immune responses. Given that antibiotic resistance is a serious challenge, new solutions are constantly being explored. The endocannabinoid system is essential for mai...



Nanostructured lipid carriers enriched hydrogels for skin topical administratio...

Lúcio, Marlene; Giannino, Nicole; Barreira, Sérgio; Catita, José; Gonçalves, Hugo; Ribeiro, Artur; Fernandes, Eduarda; Carvalho, Isabel; Pinho, Hugo

Chronic skin exposure to external hostile agents (e.g., UV radiation, microorganisms, and oxidizing chemicals) may increase oxidative stress, causing skin damage and aging. Because of their well-known skincare and protective benefits, quercetin (Q) and omega-3 fatty acids (ω3) have attracted the attention of the dermocosmetic and pharmaceutical sectors. However, both bioactives have inherent properties that lim...


Nanostructured lipid carriers enriched hydrogels for skin topical administratio...

Lúcio, M.; Giannino, Nicole; Barreira, Sérgio; Catita, José; Gonçalves, Hugo; Ribeiro, Artur; Fernandes, Eduarda; Carvalho, Isabel; Pinho, Hugo

Chronic skin exposure to external hostile agents (e.g., UV radiation, microorganisms, and oxidizing chemicals) may increase oxidative stress, causing skin damage and aging. Because of their well-known skincare and protective benefits, quercetin (Q) and omega-3 fatty acids (ω3) have attracted the attention of the dermocosmetic and pharmaceutical sectors. However, both bioactives have inherent properties that lim...


Effect of extraction methodology on the phytochemical composition for camelia s...

Barreira, Sérgio; Silva, André M. N.; Moutinho, Carla; Seo, Ean-Jeong; Hegazy, Mohamed-Elamir F.; Efferth, Thomas; Gomes, Lígia Rebelo

(1) Background: beverages based on extracts from Camellia sinensis are popular worldwide. Due to an increasing number of processed teas on the market, there is a need to develop unified classification standards based on chemical analysis. Meanwhile, phytochemical characterizations are mainly performed on tea samples from China (~80%). Hence, data on teas of other provenances is recommended. (2) Methods: in the ...


Effect of extraction methodology on the phytochemical composition for camelia s...

Barreira, Sérgio; Silva, André M. N.; Moutinho, Carla; Seo, Ean-Jeong; Hegazy, Mohamed-Elamir F.; Efferth, Thomas; Gomes, Lígia Rebelo

Background: beverages based on extracts from Camellia sinensis are popular worldwide. Due to an increasing number of processed teas on the market, there is a need to develop unified classification standards based on chemical analysis. Meanwhile, phytochemical characterizations are mainly performed on tea samples from China (~80%). Hence, data on teas of other provenances is recommended. (2) Methods: in the pres...


Phytochemical characterization and biological activities of green tea (Camellia...

Barreira, Sérgio; Moutinho, Carla; Silva, André M.N.; Neves, José Manuel Gomes da Silva; Seo, Ean-Jeong; Hegazy, Mohamed-Elamir F.; Efferth, Thomas

Background: Green tea is not only one of the most widely consumed beverages worldwide, but is also known for its health promoting and therapeutic effects. Green tea is cultivated in areas with high humidity and acidic soils in China, Indonesia and Japan. Those places have well-marked dry and rainy seasons. In opposite, Azores have a climate with constant average annual rainfall and, unlike eastern regions, rela...


Phytochemical characterization and biological activities of green tea (Camellia...

Barreira, Sérgio; Moutinho, Carla; Silva, André M.N.; Neves, José Manuel Gomes da Silva; Seo, Ean-Jeong; Hegazy, Mohamed-Elamir F.; Efferth, Thomas

Background: Green tea is not only one of the most widely consumed beverages worldwide, but is also known for its health promoting and therapeutic effects. Green tea is cultivated in areas with high humidity and acidic soils in China, Indonesia and Japan. Those places have well-marked dry and rainy seasons. In opposite, Azores have a climate with constant average annual rainfall and, unlike eastern regions, rela...


Avocado and its by-products: natural sources of nutrients, phytochemical compou...

Ferreira da Vinha, Ana; Silva, Carla Sousa e; Soares, Marta De Oliveira; Barreira, Sérgio

Avocado (Persea americana Mill.) is a tropical and subtropical fruit that is native to Mexico and Central America. This fruit is gaining increasing worldwide acceptance and has received extensive marketing and a wide distribution due to its relevant nutritional benefits for human health. This work presents relevant information on the production, composition and application of avocado, with an emphasis on its by...


Impact of boiling on phytochemicals and antioxidant activity of green vegetable...

Ferreira da Vinha, Ana; Alves, Rita C.; Barreira, Sérgio; Costa, Anabela S.G.; Oliveira, M. Beatriz P.P.

The effect of boiling (10 minutes) on eleven green vegetables frequently consumed in the Mediterranean diet was evaluated. For that, some physicochemical parameters and the contents of vitamin C, phenolics and carotenoids, as well as the antioxidant activity, were determined in raw and boiled samples. The raw vegetables analysed in this study were good sources of vitamin C, carotenoids and phenolic compounds, w...


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