9 documents found, page 1 of 1
Docking, synthesis and antiproliferative activity of N-acylhydrazone derivative...
Amaral, Daniel Nascimento do; Cavalcanti, Bruno C.; Bezerra, Daniel P.; Ferreira, Paulo Michel P.; Castro, Rosane de Paula; Sabino, José RicardoCancer is the second most common cause of death in the USA. Among the known classes of anticancer agents, the microtubule-targeted antimitotic drugs are considered to be one of the most important. They are usually classified into microtubule-destabilizing (e.g., Vinca alkaloids) and microtubule-stabilizing (e.g., paclitaxel) agents. Combretastatin A4 (CA- 4), which is a natural stilbene isolated from Combretum ...
OS produtos naturais e a química medicinal moderna
Viegas Jr., Cláudio [UNESP]; Bolzani, Vanderlan da Silva [UNESP]; Barreiro, Eliezer J.Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:21:49Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:45:38Z : No. of bitstreams: 1 2-s2.0-33645658773.pdf: 774703 bytes, checksum: c17363a0ef996fcb8dc7a1bc30b30415 (MD5); Made available in DSpace on 2014-05-27T11:21:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-03-01; Natural products have been utilized...
Aspectos químicos, biológicos e etnofarmacológicos do gênero Cassia
Viegas Jr., Cláudio [UNESP]; De Rezende, Amanda [UNESP]; Silva, Dulce Helena Siqueira [UNESP]; Bolzani, Ian Castro-Gambôa E Vanderlan Da Silva [UNESP]Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:22:01Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:44:26Z : No. of bitstreams: 1 2-s2.0-33845784790.pdf: 344098 bytes, checksum: 415badcc07b2c8b8c843484c4842fdef (MD5); Made available in DSpace on 2014-05-27T11:22:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-11-01; Species of Cassia are widely distri...
Biodiversidade: fonte potencial para a descoberta de fármacos
Barreiro, Eliezer J.; Bolzani, Vanderlan da Silva [UNESP]Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:48:46Z No. of bitstreams: 1 S0100-40422009000300012.pdf: 357363 bytes, checksum: 6b97221a7479a3bc0e7f6769a335ff49 (MD5); Made available in DSpace on 2013-08-22T18:48:47Z (GMT). No. of bitstreams: 1 S0100-40422009000300012.pdf: 357363 bytes, checksum: 6b97221a7479a3bc0e7f6769a335ff49 (MD5) Previous issue date: 2009-01-01; Made availabl...
Molecular Docking and Molecular Dynamic Studies of Semi-Synthetic Piperidine Al...
Danuello, Amanda [UNESP]; Romeiro, Nelilma C.; Giesel, Guilherme M.; Pivatto, Marcos [UNESP]; Viegas, Claudio; Verli, Hugo; Barreiro, Eliezer J.Made available in DSpace on 2013-08-12T19:20:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-01-01; Made available in DSpace on 2013-09-30T19:09:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-01-01; Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T14:20:16Z No. of bitstreams: 0; Made available in DSpace on 2014-05-20T14:20:16Z (GMT). No. of bitstreams:...
Produtos naturais como candidatos a fármacos úteis no tratamento do mal de Alzh...
Viegas Jr., Cláudio [UNESP]; Bolzani, Vanderlan da Silva [UNESP]; Furlan, Maysa [UNESP]; Manssour Fraga, Carlos Alberto; Barreiro, Eliezer J.Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:21:06Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:34:08Z : No. of bitstreams: 1 2-s2.0-15044356788.pdf: 794623 bytes, checksum: e3c06c97e6640dcfa2be44ebbc3b0d88 (MD5); Made available in DSpace on 2014-05-27T11:21:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2004-07-01; Alzheimer's disease (AD) is a progr...
Pharmaceutical sciences scenario in CNPq research fellowship
Guterres, Silvia Stanisçuaski; Lopes, João Luis Callegari; Barreiro, Eliezer J.; Mello, João Carlos Palazzo de
Therapeutic approaches for tumor necrosis factor inhibition
Barbosa, Maria Letícia de Castro; Fumian, Milla Machado; Miranda, Ana Luísa Palhares de; Barreiro, Eliezer J.; Lima, Lídia MoreiraTumor necrosis factor (TNF) consists of an inflammatory cytokine essential for homeostasis and organism defense. Despite its physiological relevance, both increased biosynthesis and release of TNF lead to the exacerbation of inflammatory and oxidative responses, which are related to the pathogenesis of a host of diseases of an inflammatory, autoimmune and/or infectious nature. In this context, effective therape...
Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally ef...
Barreiro, Eliezer J.