11 documents found, page 1 of 2
Avaliação do desempenho de uma core-facility de sequenciação genómica especiali...
Vieira, Luís; Silva, Catarina; Duarte, Sílvia; Mendonça, Joana; Carpinteiro, Dina; Sampaio, Daniel A.; Ferrão, José; Santos, Daniela; Machado, MiguelA Unidade de Tecnologia e Inovação (UTI) do Departamento de Genética Humana foi criada em 2009 pelo despacho normativo n.º 15/2009. Apesar de estar integrada num departamento técnico científico, esta unidade constituiu-se desde logo como core-facility de sequenciação genómica do Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA). Este papel envolve uma gestão contínua de prioridades dos serviços a prestar ...
The Technology and Innovation Unit of the National Institute of Health: A seque...
Silva, Catarina; Ataíde Sampaio, Daniel; Mendonça, Joana; Carpinteiro, Dina; Duarte, Sílvia; Barreiro, Paula; Isidro, Joana; Machado, MiguelThe National Institute of Health (INSA) has a long tradition in investigating the molecular etiology of genetic and complex diseases. These activities greatly benefit from centralized sequencing services provided by the Technology and Innovation Unit (UTI). Its mission is to perform sequencing and genotyping assays in the framework of research, diagnosis and epidemiological surveillance, as well as to implement...
The Technology and Innovation Unit of the National Institute of Health: a seque...
Silva, Catarina; Ataíde Sampaio, Daniel; Mendonça, Joana; Carpinteiro, Dina; Duarte, Sílvia; Barreiro, Paula; Isidro, Joana; Machado, MiguelThe National Institute of Health (INSA) is the state laboratory in the health sector. INSA has a long tradition in investigating the molecular etiology of genetic and complex diseases and in the identification of pathogenic organisms responsible for disease outbreaks and environmental imbalances. These activities benefit greatly from the existing centralized sequencing services provided by the Technology and In...
A large outbreak of Legionnaires’ Disease in an industrial town in Portugal
George, Francisco; Shivaji, Tara; Pinto, Catia Sousa; Serra, Luis Antonio Oliveira; Valente, João; Albuquerque, Maria JoãoBackground: We describe the investigation and control of an outbreak of Legionnaires’ disease in Portugal in October, November and December 2014. Methods: Confirmed cases were individuals with pneumonia, laboratory evidence of Legionella pneumophila serogroup 1 and exposure, by residence, occupational or leisure to the affected municipalities. 49 possible sources were reduced to four potential sources, all indu...
Architecture of Class 1, 2, and 3 Integrons from Gram Negative Bacteria Recover...
Jones-Dias, Daniela; Manageiro, Vera; Ferreira, Eugénia; Barreiro, Paula; Vieira, Luís; Moura, Inês B; Caniça, ManuelaThe spread of antibiotic resistant bacteria throughout the food chain constitutes a public health concern. To understand the contribution of fresh produce in shaping antibiotic resistance bacteria and integron prevalence in the food chain, 333 antibiotic resistance Gram negative isolates were collected from organic and conventionally produced fruits (pears, apples, and strawberries) and vegetables (lettuces, to...
A large outbreak of Legionnaires’ Disease in an industrial town in Portugal
George, Francisco; Shivaji, Tara; Pinto, Catia Sousa; Serra, Luis Antonio Oliveira; Valente, João; Albuquerque, Maria JoãoABSTRACT - Background: We describe the investigation and control of an outbreak of Legionnaires’ disease in Portugal in October, November and December 2014. Methods: Confirmed cases were individuals with pneumonia, laboratory evidence of Legionella pneumophila serogroup 1 and exposure, by residence, occupational or leisure to the affected municipalities. 49 possible sources were reduced to four potential source...
A large outbreak of Legionnaires’ Disease in an industrial town in Portugal
George, Francisco; Shivaji, Tara; Pinto, Catia Sousa; Serra, Luis Antonio Oliveira; Valente, João; Albuquerque, Maria JoãoA B S T R A C T - Background: We describe the investigation and control of an outbreak of Legionnaires’ disease in Portugal in October, November and December 2014. Methods: Confirmed cases were individuals with pneumonia, laboratory evidence of Legionella pneumophila serogroup 1 and exposure, by residence, occupational or leisure to the affected municipalities. 49 possible sources were reduced to four potential...
A gripe em Portugal: análise preliminar da atividade gripal 2014/2015
Pechirra, Pedro; Cristóvão, Paula; Costa, Inês; Roque, Carla; Barreiro, Paula; Duarte, Sílvia; Machado, Ausenda; Rodrigues, Ana Paula; Nunes, BaltazarObjetivo: Pretende-se com a presente publicação, divulgar a análise preliminar da atividade gripal em Portugal na época de 2014/2015 (entre 15 de setembro de 2014 e 20 de março de 2015).
Influenza in Portugal, 2014/2015 season
Pechirra, Pedro; Cristóvão, Paula; Costa, Inês; Roque, Carla; Barreiro, Paula; Duarte, Sílvia; Machado, Ausenda; Rodrigues, Ana Paula; Nunes, BaltazarDuring 2014/2015 season the influenza activity was high, the epidemic period was observed between week 1/2015 and 8/2015 with a maximum of 148 ILI cases per 105 inhabitants in week 4/2015. The influenza B virus, A(H3) and A(H1)pdm09 co-circulated during the season, although influenza B were dominant throughout the winter, except for weeks 4, 6 and 7/2015 where it was detected in co-dominance with influenza A vi...
Caraterização virológica dos vírus da gripe que circularam em Portugal na época...
Pechirra, Pedro; Costa, Inês; Cristóvão, Paula; Roque, Carla; Barreiro, Paula; Duarte, Sílvia; Machado, Ausenda; Rodrigues, Ana Paula; Nunes, BaltazarIntrodução e objetivo: A monitorização contínua das propriedades antigénicas e genéticas dos vírus da gripe é essencial, quer para a seleção anual das estirpes virais a incluir na vacina, quer para identificar novas linhas de orientação da terapêutica antiviral. O presente estudo descreve as caraterísticas antigénicas e genéticas dos vírus da gripe identificados em Portugal no inverno de 2014/2015.